Il2ra Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il2ra
interleukin 2 receptor, alpha chain
MGI:96549

65 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il2ra^M1J/Il2ra^M1J involves: 129S4/SvJae * C57BL/6	abnormal regulatory T cell physiology	J:268677
Il2ra^{tm1b(EUCOMM)Wtsi}/Il2ra^{tm1b(EUCOMM)Wtsi} C57BL/6N-Il2ra^{tm1b(EUCOMM)Wtsi}/Orl	abnormal cholesterol homeostasis	J:211773
	abnormal colon morphology	J:211773
	abnormal contextual conditioning behavior	J:211773
	abnormal duodenum morphology	J:211773
	abnormal freezing behavior	J:211773
	abnormal locomotor behavior	J:211773
	abnormal spleen morphology	J:211773
	abnormal vertebrae morphology	J:211773
	decreased blood urea nitrogen level	J:211773
	decreased body length	J:211773
	decreased bone mineral density	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased circulating calcium level	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased circulating total protein level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased exploration in new environment	J:211773
	decreased heart weight	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	decreased locomotor activity	J:211773
	decreased lymphocyte cell number	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	decreased mean corpuscular volume	J:211773
	decreased vertical activity	J:211773
	enlarged lymph nodes	J:211773
	improved glucose tolerance	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating phosphate level	J:211773
	increased large unstained cell number	J:211773
	increased neutrophil cell number	J:211773
	prolonged PR interval	J:211773
Il2ra^tm1Dw/Il2ra^tm1Dw B6.129S4-Il2ra^tm1Dw	abnormal induced morbidity/mortality	J:125748
	abnormal regulatory T cell physiology	J:125748
	abnormal T cell activation	J:125748
	anemia	J:125748
	decreased body size	J:125748
	lymphoid hyperplasia	J:125748
Il2ra^tm1Dw/Il2ra^tm1Dw B6.129S4-Il2ra^tm1Dw/J	abnormal salivary gland duct morphology	J:125129
	abnormal salivary gland morphology	J:125129
	decreased salivation	J:125129
	lacrimal gland inflammation	J:125129
	large intestinal inflammation	J:125129
	lung inflammation	J:125129
	salivary gland inflammation	J:125129
Il2ra^tm1Dw/Il2ra^tm1Dw involves: 129S4/SvJae * C57BL/6	abnormal B cell physiology	J:64279
	abnormal lymph organ size	J:64279
	abnormal T cell morphology	J:64279
	abnormal T cell physiology	J:64279
	cachexia	J:64279
	colitis	J:64279
	decreased hematocrit	J:64279
	diarrhea	J:64279
	enlarged lymph nodes	J:64279
	enlarged spleen	J:64279
	hemolytic anemia	J:64279
	increased IgA level	J:64279
	increased IgG1 level	J:64279
	increased IgG2a level	J:64279
	increased IgG2b level	J:64279
	increased IgG level	J:64279
	increased lymphocyte cell number	J:64279
	increased memory T cell number	J:64279
	premature death	J:64279

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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