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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Il7
interleukin 7
MGI:96561
47 phenotypes from 8 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Il7hlb368/Il7hlb368
C57BL/6J-Il7hlb368/J 		abnormal T cell subpopulation ratio J:118450
absent axillary lymph nodes J:118450
absent cervical lymph nodes J:118450
absent mesenteric lymph nodes J:118450
absent Peyer's patches J:118450
absent popliteal lymph nodes J:118450
decreased leukocyte cell number J:82961, J:118450
decreased T cell number J:118450
small inguinal lymph nodes J:118450
small spleen J:118450
small thymus J:118450
spleen hypoplasia J:118450
thymus hypoplasia J:118450
Il7m1Jyen/Il7m1Jyen
involves: C3H * C57BL/6 		abnormal myeloid leukocyte morphology J:136470
decreased B cell number J:136470
decreased single-positive T cell number J:136470
lymph node hypoplasia J:136470
spleen hypoplasia J:136470
thymus hypoplasia J:136470
Il7tm1.1Mysl/Il7+
B6.129P2(Cg)-Il7tm1.1Mysl 		decreased T cell number J:200544
small lymph nodes J:200544
Il7tm1.1Mysl/Il7tm1.1Mysl
B6.129P2(Cg)-Il7tm1.1Mysl 		abnormal mesenteric lymph node morphology J:200544
arrested B cell differentiation J:200544
decreased T cell number J:200544
decreased thymocyte number J:200544
normal immune system phenotype J:200544
small lymph nodes J:200544
thymus hypoplasia J:200544
Il7tm1Dnax/Il7tm1Dnax
involves: 129P2/OlaHsd 		decreased thymocyte number J:64861
Il7tm1Dnax/Il7tm1Dnax
involves: 129P2/OlaHsd * C57BL/6 		abnormal CD8-positive, alpha beta T cell morphology J:125259
absent lymph nodes J:24165
absent Peyer's patches J:24165
arrested B cell differentiation J:24165
decreased lymphocyte cell number J:24165
decreased spleen weight J:24165
decreased thymus weight J:24165
small spleen J:24165
small thymus J:24165
spleen hypoplasia J:24165
thymus hypoplasia J:24165
Il7tm1Hms/Il7tm1Hms
involves: 129S6/SvEvTac 		decreased bone marrow cell number J:43971
spleen hypoplasia J:43971
thymus hypoplasia J:43971
Il7tm2.1Iku/Il7tm2.1Iku
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA 		abnormal B cell differentiation J:190615
abnormal NK T cell physiology J:190615
decreased B cell number J:190615
decreased double-negative T cell number J:190615
decreased lymphocyte cell number J:190615
decreased NK T cell number J:190615
decreased T cell number J:190615
normal hematopoietic system phenotype J:190615
normal immune system phenotype J:190615
Tg(H2-Ea-Il7)10Rhdr/0
involves: C57BL/6 		abnormal B cell morphology J:81133
abnormal double-negative T cell morphology J:81133
Tg(H2-Ea-Il7)10Rhdr/0
involves: C57BL/6 * DBA/2 		increased pre-B cell number J:171924
increased pro-B cell number J:171924
Tg(KRT14-Il7)1Tsk/0
FVB/N-Tg(KRT14-Il7)1Tsk 		alopecia J:42565
blepharitis J:42565
delayed eyelid opening J:42565
reddish skin J:42565
skin inflammation J:42565
thick ears J:42565
Tg(KRT14-Il7)1Tsk/Tg(KRT14-Il7)1Tsk
FVB/N-Tg(KRT14-Il7)1Tsk 		alopecia J:42565
decreased body size J:42565
infertility J:42565
premature death J:42565
skin inflammation J:42565
Tg(KRT14-Il7)1Tsk/Tg(KRT14-Il7)1Tsk
involves: C57BL/6 * FVB 		alopecia J:42565
decreased survivor rate J:42565
infertility J:42565
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory