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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Itga1
integrin alpha 1
MGI:96599
18 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Col4a3tm1Dec/Col4a3tm1Dec
Itga1tm1Gdnr/Itga1tm1Gdnr
involves: 129S4/SvJae * 129X1/SvJ * BALB/c 		abnormal kidney morphology J:71378
abnormal renal glomerulus basement membrane morphology J:91620
increased circulating total protein level J:91620
kidney failure J:91620
tubular nephritis J:71378
Ins2Akita/Ins2Akita
Itga1tm1Gdnr/Itga1tm1Gdnr
C.Cg-Ins2Akita Itga1tm1Gdnr 		abnormal glomerular capillary morphology J:198186
abnormal glomerular mesangium morphology J:198186
abnormal kidney interstitium morphology J:198186
albuminuria J:198186
decreased body weight J:198186
expanded mesangial matrix J:198186
glomerulosclerosis J:198186
hyperglycemia J:198186
increased renal glomerular filtration rate J:198186
increased renal glomerulus basement membrane thickness J:198186
mesangiolysis J:198186
premature death J:198186
renal glomerular protein deposits J:198186
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory