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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Itga2b
integrin alpha 2b
MGI:96601
21 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Itga2btm1(GFP/cre)Emam/Itga2btm1(GFP/cre)Emam
involves: 129S6/SvEvTac * C57BL/6 		abnormal cell adhesion J:84564
abnormal definitive hematopoiesis J:84564
abnormal embryonic hematopoiesis J:84564
abnormal platelet physiology J:84564
anemia J:84564
increased hematopoietic stem cell number J:84564
thrombocytopenia J:84564
Itga2btm1Graf/Itga2b+
B6.Cg-Itga2btm1Graf 		abnormal platelet activation J:123159
thrombocytopenia J:123159
Itga2btm1Graf/Itga2btm1Graf
B6.Cg-Itga2btm1Graf 		normal reproductive system phenotype J:123159
Itga2btm1Tlr/Itga2b+
either: (involves: 129S1/Sv * 129X1/SvJ * BALB/c) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal platelet activation J:63961
abnormal platelet aggregation J:63961
abnormal platelet physiology J:63961
Itga2btm1Tlr/Itga2btm1Tlr
either: (involves: 129S1/Sv * 129X1/SvJ * BALB/c) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal blood coagulation J:63961
abnormal hemostasis J:63961
abnormal platelet activation J:63961
abnormal platelet alpha-granule morphology J:63961
abnormal platelet physiology J:63961
decreased erythrocyte cell number J:63961
decreased platelet aggregation J:63961
enlarged spleen J:63961
gastrointestinal hemorrhage J:63961
hemorrhage J:63961
increased bleeding time J:63961
internal hemorrhage J:63961
normal reproductive system phenotype J:63961
subcutaneous hemorrhage J:63961
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory