Itga2b Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itga2b
integrin alpha 2b
MGI:96601

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Itga2b^{tm1(GFP/cre)Emam}/Itga2b^{tm1(GFP/cre)Emam} Rhoa^tm1Csab/Rhoa^tm1Csab Tg(ITGA2B)3Mako/0 Tg(Pf4-icre)Q3Rsko/0 involves: 129S6/SvEvTac * C57BL/6	abnormal megakaryocyte differentiation	J:204459
	abnormal megakaryocyte morphology	J:204459
	decreased megakaryocyte cell number	J:204459
Itga2b^tm1Graf/Itga2b^tm1Graf Tfpi^tm1Gjb/Tfpi^tm1Gjb involves: 129 * C57BL/6J * SJL	domed cranium	J:283423
	enlarged brain ventricles	J:283423
	hydrocephaly	J:283423
	premature death	J:283423
	preweaning lethality, incomplete penetrance	J:283423
Itga2b^tm1Tlr/Itga2b^tm1Tlr Vwf^tm1.1Diac/Vwf^tm1.1Diac involves: 129S1/Sv * 129X1/SvJ	normal homeostasis/metabolism phenotype	J:181672

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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