Itga5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itga5
integrin alpha 5 (fibronectin receptor alpha)
MGI:96604

21 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itga5^tm1Hyn/Itga5^tm1Hyn involves: 129S2/SvPas * C57BL/6J	abnormal blood vessel morphology	J:16248
	abnormal dorsal aorta morphology	J:16248
	abnormal embryonic tissue morphology	J:16248
	abnormal extraembryonic mesoderm development	J:16248
	abnormal extraembryonic tissue morphology	J:16248
	abnormal rostral-caudal axis patterning	J:16248
	abnormal vitelline vasculature morphology	J:16248
	caudal body truncation	J:16248
	normal cellular phenotype	J:16248
	decreased paraxial mesoderm size	J:16248
	embryonic growth retardation	J:16248
	embryonic lethality during organogenesis, complete penetrance	J:16248
	incomplete embryo turning	J:16248
	incomplete somite formation	J:16248
	kinked neural tube	J:16248
	short rostral-caudal axis	J:16248
Itga5^tm1Hyn/Itga5^tm2Hyn Tg(Tek-cre)1Ywa/0 involves: 129 * C57BL/6 * SJL	no abnormal phenotype detected	J:161850
Itga5^tm2.1Hyn/Itga5^tm2.1Hyn involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal blood vessel morphology	J:161850
	embryonic growth retardation	J:161850
	embryonic lethality during organogenesis, complete penetrance	J:161850
	incomplete somite formation	J:161850
Itga5^tm2Hyn/Itga5^tm2Hyn involves: 129S1/Sv * 129X1/SvJ	abnormal cerebral cortex morphology	J:159465
Itga5^tm2Hyn/Itga5^tm2Hyn involves: 129S1/Sv * 129X1/SvJ	abnormal neuronal migration	J:159465
Itga5^tm2Hyn/Itga5^tm2Hyn Tg(Tek-cre)1Ywa/0 B6.Cg-Tg(Tek-cre)1Ywa Itga5^tm2Hyn	patent ductus arteriosus	J:161850
	postnatal lethality, incomplete penetrance	J:161850

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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