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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Itga5
integrin alpha 5 (fibronectin receptor alpha)
MGI:96604
21 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Itga5tm1Hyn/Itga5tm1Hyn
involves: 129S2/SvPas * C57BL/6J 		abnormal blood vessel morphology J:16248
abnormal dorsal aorta morphology J:16248
abnormal embryonic tissue morphology J:16248
abnormal extraembryonic mesoderm development J:16248
abnormal extraembryonic tissue morphology J:16248
abnormal rostral-caudal axis patterning J:16248
abnormal vitelline vasculature morphology J:16248
caudal body truncation J:16248
normal cellular phenotype J:16248
decreased paraxial mesoderm size J:16248
embryonic growth retardation J:16248
embryonic lethality during organogenesis, complete penetrance J:16248
incomplete embryo turning J:16248
incomplete somite formation J:16248
kinked neural tube J:16248
short rostral-caudal axis J:16248
Itga5tm1Hyn/Itga5tm2Hyn
Tg(Tek-cre)1Ywa/0
involves: 129 * C57BL/6 * SJL 		no abnormal phenotype detected J:161850
Itga5tm2.1Hyn/Itga5tm2.1Hyn
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal blood vessel morphology J:161850
embryonic growth retardation J:161850
embryonic lethality during organogenesis, complete penetrance J:161850
incomplete somite formation J:161850
Itga5tm2Hyn/Itga5tm2Hyn
involves: 129S1/Sv * 129X1/SvJ 		abnormal cerebral cortex morphology J:159465
abnormal neuronal migration J:159465
Itga5tm2Hyn/Itga5tm2Hyn
Tg(Tek-cre)1Ywa/0
B6.Cg-Tg(Tek-cre)1Ywa Itga5tm2Hyn 		patent ductus arteriosus J:161850
postnatal lethality, incomplete penetrance J:161850
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory