Itga6 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itga6
integrin alpha 6
MGI:96605

35 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Itga3^tm1Hap/Itga3^tm1Hap Itga6^tm2Egl/Itga6^tm2Egl Tg(Mpz-cre)26Mes/0 involves: 129 * C57BL/6 * FVB/NTac	normal nervous system phenotype	J:204174
Itga3^tm1Jak/Itga3^tm1Jak Itga6^tm1Egl/Itga6^tm1Egl involves: 129S2/SvPas * 129S4/SvJae	abnormal apical ectodermal ridge morphology	J:56564
	abnormal autopod morphology	J:56564
	abnormal choroid plexus morphology	J:56564
	abnormal digit development	J:56564
	abnormal epidermal layer morphology	J:56564
	abnormal left lung morphology	J:56564
	abnormal lens epithelium morphology	J:56564
	abnormal Mullerian duct morphology	J:56564
	abnormal neural tube closure	J:56564
	abnormal primitive urogenital sinus morphology	J:56564
	abnormal rectum morphology	J:56564
	abnormal retina nerve fiber layer morphology	J:56564
	abnormal right lung morphology	J:56564
	abnormal stratification in cerebral cortex	J:56564
	abnormal vitreous body morphology	J:56564
	abnormal Wolffian duct morphology	J:56564
	absent ureter	J:56564
	absent urinary bladder	J:56564
	disorganized retina ganglion layer	J:56564
	fetal growth retardation	J:56564
	impaired branching involved in terminal bronchiole morphogenesis	J:56564
	impaired lung lobe morphogenesis	J:56564
	lethality throughout fetal growth and development, complete penetrance	J:56564
	oligodactyly	J:56564
	pancreas hypoplasia	J:56564
	pulmonary hypoplasia	J:56564
	syndactyly	J:56564
	urethra atresia	J:56564
Itga6^tm2Egl/Itga6^tm2Egl Itga7^tm1Umr/Itga7^tm1Umr Tg(Mpz-cre)26Mes/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/NTac	abnormal axon radial sorting	J:204174
	abnormal myelination	J:204174
	abnormal Schwann cell physiology	J:204174
	abnormal sciatic nerve morphology	J:204174
	axon degeneration	J:204174
	hypermyelination	J:204174

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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