Itgb2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itgb2
integrin beta 2
MGI:96611

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Itgav^tm1Blb/Itgav^tm1Blb Itgb1^tm1Ref/Itgb1^tm1Ref Itgb2^tm2Bay/Itgb2^tm2Bay Itgb7^tm1Cgn/Itgb7^tm1Cgn Tg(Mx1-cre)1Cgn/0 involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * CBA	abnormal cellular extravasation	J:134784
	abnormal dendritic cell physiology	J:134784
	normal immune system phenotype	J:134784
Itgb2^tm1Bay/Itgb2^tm1Bay Psrs1^PL/J/Psrs1^PL/J B6.Cg-(D10Mit75-D10Mit271) Itgb2^tm1Bay	psoriasis	J:134251
	rheumatoid arthritis	J:134251
Itgb2^tm1Bay/Itgb2^tm1Bay Psrs1^PL/J/Psrs1^PL/J B6.Cg-(D10Mit126-D10Mit38) Itgb2^tm1Bay	psoriasis	J:134251
	rheumatoid arthritis	J:134251
Itgb2^tm1Bay/? Psrs1^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs2^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs3^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs4^PL/J/? involves: C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs4^PL/J/Psrs4^PL/J Psrs6^PL/J/Psrs6^PL/J involves: C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs5^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Itgb2^tm1Bay/? Psrs7^PL/J/? involves: 129S7/SvEvBrd * C57BL/6J * PL/J	psoriasis	J:117544
Ptpn6^me-v/Ptpn6^me-v involves: 129S7/SvEvBrd * C57BL/6J	decreased retina photoreceptor cell number	J:108375
Ptpn6^me-v/Ptpn6^me-v involves: 129S7/SvEvBrd * C57BL/6J	retina photoreceptor degeneration	J:108375
Rhoh^tm1Brak/Rhoh^tm1Brak Itgb2^tm2Bay/Itgb2^tm2Bay involves: 129/Sv * C57BL/6	decreased CD4-positive, alpha-beta T cell number	J:143161
	decreased CD8-positive, alpha-beta T cell number	J:143161
	decreased double-positive T cell number	J:143161
	decreased single-positive T cell number	J:143161
	increased double-negative T cell number	J:143161

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24