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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Itgb3
integrin beta 3
MGI:96612
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Apoetm1Unc/Apoetm1Unc
Itgb3tm1Hyn/Itgb3tm1Hyn
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		anemia J:83615
atherosclerotic lesions J:83615
decreased susceptibility to diet-induced obesity J:83615
increased susceptibility to induced morbidity/mortality J:83615
lung inflammation J:83615
postnatal lethality, incomplete penetrance J:83615
premature death J:83615
Fbn1tm2.1Hcd/Fbn1+
Itgb3tm1Hyn/Itgb3+
involves: 129S * 129X1/SvJ * C57BL/6J * FVB/N 		abnormal cutaneous collagen fibril morphology J:206074
epidermal hyperplasia J:206074
normal integument phenotype J:206074
thick dermal layer J:206074
Fbn1tm3.1Hcd/Fbn1+
Itgb3tm1Hyn/Itgb3+
involves: 129S * 129X1/SvJ * C57BL/6J * FVB/N 		abnormal cutaneous collagen fibril morphology J:206074
epidermal hyperplasia J:206074
normal integument phenotype J:206074
thick dermal layer J:206074
Ilktm2Star/Ilk+
Itgb3tm1Hyn/Itgb3+
involves: 129S2/SvPas * C57BL/6 		increased trabecular bone thickness J:197593
Itgb3tm1Hyn/Itgb3tm1Hyn
Itgb5tm1Des/Itgb5tm1Des
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		abnormal tumor vascularization J:73752
increased tumor growth/size J:73752
Itgb3tm1Hyn/Itgb3tm1Hyn
Ldlrtm1Her/Ldlrtm1Her
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 		atherosclerotic lesions J:83615
decreased circulating cholesterol level J:83615
decreased survivor rate J:83615
increased circulating glucose level J:83615
increased susceptibility to induced morbidity/mortality J:83615
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory