Itgb4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itgb4
integrin beta 4
MGI:96613

31 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itgb4^tm1.1Mfel/Itgb4^tm1.1Mfel involves: 129S2/SvPas * C57BL/6	blistering	J:137852
Itgb4^tm1Efu/Itgb4^tm1Efu involves: 129S1/Sv * 129X1/SvJ	normal nervous system phenotype	J:77644
Itgb4^tm1Efu/Itgb4^tm1Efu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal epidermis stratum basale morphology	J:77644
	abnormal epidermis stratum spinosum morphology	J:77644
	abnormal epidermis suprabasal layer morphology	J:77644
	abnormal esophageal epithelium morphology	J:77644
	abnormal skin condition	J:77644
	abnormal skin physiology	J:77644
	abnormal tongue epithelium morphology	J:77644
	blistering	J:77644
	dermal-epidermal separation	J:77644
	neonatal lethality, complete penetrance	J:77644
	respiratory failure	J:77644
Itgb4^tm1Fgg/Itgb4^tm1Fgg involves: 129S1/Sv * C57BL/6	abnormal enterocyte proliferation	J:48924
	abnormal epidermal layer morphology	J:48924
	abnormal esophageal epithelium morphology	J:48924
	abnormal skin morphology	J:48924
	aphagia	J:48924
	blistering	J:48924
	decreased keratinocyte adhesion	J:48924
	dehydration	J:48924
	dermal-epidermal separation	J:48924
	perinatal lethality, complete penetrance	J:48924
Itgb4^tm1Mfel/Itgb4^tm1.1Mfel Tg(Mpz-cre)26Mes/0 involves: 129S2/SvPas * C57BL/6 * FVB/N	abnormal myelin sheath morphology	J:137852
	normal behavior/neurological phenotype	J:137852
Itgb4^tm1Mfel/Itgb4^tm1Mfel Tg(Mpz-cre)26Mes/0 involves: 129S2/SvPas * C57BL/6 * FVB/N	abnormal myelin sheath morphology	J:137852
	normal behavior/neurological phenotype	J:137852
Itgb4^tm1Son/Itgb4^tm1Son 129P2/OlaHsd-Itgb4^tm1Son	abnormal cornea morphology	J:33713
	abnormal keratinocyte morphology	J:33713
	abnormal nail morphology	J:33713
	abnormal olfactory epithelium morphology	J:33713
	abnormal skin condition	J:33713
	abnormal tongue epithelium morphology	J:33713
	abnormal urinary bladder urothelium morphology	J:33713
	dermal-epidermal separation	J:33713
	edema	J:33713
	normal immune system phenotype	J:33713
	neonatal lethality, complete penetrance	J:33713
	normal nervous system phenotype	J:33713
Itgb4^tm2Fgg/Itgb4^tm2Fgg involves: 129/Sv * C57BL/6	decreased angiogenesis	J:94627
Itgb4^tm2Fgg/Itgb4^tm2Fgg involves: 129/Sv * C57BL/6	normal integument phenotype	J:94627
Itgb4^tm2Son/Itgb4^tm2Son Tg(KRT14-cre)8Brn/0 involves: 129P2/OlaHsd * FVB/N	abnormal keratinocyte morphology	J:96543
	blistering	J:96543
	ear inflammation	J:96543

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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