Itgb6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itgb6
integrin beta 6
MGI:96615

27 phenotypes from 2 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itgb6^{em1(IMPC)Ccpcz}/Itgb6^{em1(IMPC)Ccpcz} C57BL/6NCrl-Itgb6^{em1(IMPC)Ccpcz}/Ccpcz	abnormal digit morphology	J:211773
	abnormal eye morphology	J:211773
	abnormal inspiratory capacity	J:211773
	abnormal skin morphology	J:211773
	abnormal thymus morphology	J:211773
	abnormal tooth color	J:211773
	abnormal tooth morphology	J:211773
	anophthalmia	J:211773
	decreased body weight	J:211773
	decreased lung elastance	J:211773
	decreased lung tissue damping	J:211773
	decreased respiratory quotient	J:211773
	enlarged thymus	J:211773
	increased circulating alanine transaminase level	J:211773
	increased lung compliance	J:211773
Itgb6^tm1Des/Itgb6^tm1Des either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6)	abnormal response/metabolism to endogenous compounds	J:109367
	decreased susceptibility to injury	J:109367
Itgb6^tm1Des/Itgb6^tm1Des involves: 129S4/SvJae	abnormal immune system physiology	J:120085
	absent Langerhans cell	J:120085
	decreased Langerhans cell number	J:120085
Itgb6^tm1Des/Itgb6^tm1Des involves: 129S4/SvJae * C57BL/6 * SJL	respiratory system inflammation	J:51592
Itgb6^tm1Des/Itgb6^tm1Des involves: 129S4/SvJae * C57BL/6J	abnormal hair follicle morphology	J:33139
	abnormal lung morphology	J:33139
	alopecia	J:33139
	decreased hair follicle number	J:33139
	respiratory system inflammation	J:33139
Itgb6^tm1Des/Itgb6^tm1Des involves: 129T2/SvEms	emphysema	J:89578
Itgb6^tm1Des/Itgb6^tm1Des involves: 129T2/SvEms	overexpanded pulmonary alveolus	J:89578

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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