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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Junb
jun B proto-oncogene
MGI:96647
48 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Junbtm1b(EUCOMM)Hmgu/Junb+
C57BL/6N-Junbtm1b(EUCOMM)Hmgu/Bay 		increased spleen weight J:211773
Junbtm1b(EUCOMM)Hmgu/Junbtm1b(EUCOMM)Hmgu
C57BL/6N-Junbtm1b(EUCOMM)Hmgu/Bay 		abnormal embryo size J:211773
abnormal embryo turning J:211773
abnormal forebrain development J:211773
abnormal hindbrain development J:211773
abnormal midbrain development J:211773
abnormal neural tube closure J:211773
abnormal neural tube morphology J:211773
embryonic growth retardation J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Junbtm3Wag/Junbtm3Wag
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6 		abnormal bone ossification J:88126
abnormal osteoclast morphology J:88126
abnormal trabecular bone morphology J:88126
Junbtm3Wag/Junbtm3Wag
Meox2tm1(cre)Sor/Meox2+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 		abnormal bone ossification J:88126
abnormal osteoclast differentiation J:88126
abnormal skeleton development J:88126
abnormal skeleton physiology J:88126
decreased bone mineral density J:88126
decreased bone resorption J:88126
decreased bone strength J:88126
decreased compact bone thickness J:88126
decreased osteoblast cell number J:88126
decreased osteoclast cell number J:88126
increased chronic myelocytic leukemia incidence J:88126
short tibia J:88126
Junbtm3Wag/Junbtm3Wag
Tg(KRT5-cre)1Tak/0
involves: 129/Sv * 129P2/OlaHsd * C3H * C57BL/6 		abnormal epidermal-dermal junction morphology J:155575
abnormal glomerular capillary morphology J:155575
albuminuria J:155575
dermatitis J:155575
glomerulonephritis J:155575
increased anti-histone antibody level J:155575
increased circulating interleukin-6 level J:155575
increased IgE level J:155575
increased inflammatory response J:155575
increased interleukin-6 secretion J:155575
increased mesangial cell number J:155575
increased plasma cell number J:155575
increased renal glomerulus basement membrane thickness J:155575
increased renal glomerulus lobularity J:155575
increased susceptibility to systemic lupus erythematosus J:155575
kidney atrophy J:155575
podocyte foot process effacement J:155575
premature death J:155575
renal glomerular immunoglobulin deposits J:155575
small kidney J:155575
spontaneous skin ulceration J:155575
thick skin J:155575
tubulointerstitial nephritis J:155575
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory