Kcnb1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
MGI:96666

18 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcnb1^{tm1b(EUCOMM)Hmgu}/Kcnb1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Kcnb1^{tm1b(EUCOMM)Hmgu}/H	abnormal gait	J:211773
	abnormal locomotor behavior	J:211773
	hyperactivity	J:211773
	increased exploration in new environment	J:211773
	increased lean body mass	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular volume	J:211773
Kcnb1^tm1Dgen/Kcnb1^tm1Dgen involves: C57BL/6	abnormal pancreatic beta cell physiology	J:129963
	hypoglycemia	J:129963
	improved glucose tolerance	J:129963
	increased circulating insulin level	J:129963
	increased insulin secretion	J:129963
Kcnb1^tm1Dgen/Kcnb1^tm1Dgen involves: C57BL/6N	abnormal cone electrophysiology	J:279816
	abnormal rod electrophysiology	J:279816
	decreased total retina thickness	J:279816
	short photoreceptor inner segment	J:279816
	short photoreceptor outer segment	J:279816
	thin retina outer nuclear layer	J:279816

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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