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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kit
KIT proto-oncogene receptor tyrosine kinase
MGI:96677
98 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
a/a
KitW-2J/Kit+
involves: C57BL/6J 		white spotting J:192797
Adamts20bt-2H/Adamts20bt-2H
Kittm1Alf/Kit+
involves: 129S2/SvPas * C57BL/6 		belted J:133403
white spotting J:133403
Adamts20bt-2H/Adamts20bt-2H
Kittm1Alf/Kittm1Alf
involves: 129S2/SvPas * C57BL/6 		belted J:133403
white spotting J:133403
Amhr2tm3(cre)Bhr/Amhr2+
KitW-v/KitW-v
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N 		increased granulosa cell tumor incidence J:236161
increased ovary adenoma incidence J:236161
increased ovary tumor incidence J:236161
Cdkn1btm1Ako/Cdkn1b+
KitW-v/KitW-v
involves: 129S1/Sv * C57BL/6J 		abnormal ovary physiology J:236161
increased ovary adenoma incidence J:236161
increased ovary tumor incidence J:236161
premature death J:236161
Cdkn1btm1Ako/Cdkn1btm1Ako
KitW-v/KitW-v
involves: 129S1/Sv * C57BL/6J 		abnormal ovary physiology J:236161
increased ovary adenoma incidence J:236161
increased ovary tumor incidence J:236161
f/f+
KitW/Kit+
FL/1Re-KitW/J 		white spotting J:24610
f/f
KitW/Kit+
FL/1Re-KitW/J 		abnormal erythrocyte cell number J:24610
decreased body weight J:24610
decreased hematocrit J:24610
decreased mean corpuscular volume J:24610
white spotting J:24610
Fbn1Tsk/Fbn1+
KitW/Kit+
involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ 		diluted coat color J:24076
skin fibrosis J:24076
tight skin J:24076
variable body spotting J:24076
Fbn1Tsk/Fbn1+
KitW/KitW-v
involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ 		abnormal hypodermis morphology J:24076
absent coat pigmentation J:24076
absent mast cells J:24076
anemia J:24076
overexpanded pulmonary alveolus J:24076
skin fibrosis J:24076
tight skin J:24076
Flt3tm1Irl/Flt3tm1Irl
KitW/KitW-v
involves: 129S/SvEv * C57BL/6 		abnormal blood cell morphology/development J:27238
abnormal common myeloid progenitor cell morphology J:27238
abnormal leukocyte morphology J:27238
abnormal myelopoiesis J:27238
abnormal T cell number J:27238
decreased B cell number J:27238
decreased body weight J:27238
decreased bone marrow cell number J:27238
decreased double-negative T cell number J:27238
decreased double-positive T cell number J:27238
decreased lymphocyte cell number J:27238
decreased pre-B cell number J:27238
decreased pro-B cell number J:27238
thymus hypoplasia J:27238
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
Kittm1(cre/ERT2)Dsa/Kit+
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 		abnormal gastrointestinal motility J:204737
abnormal intestinal peristalsis J:204737
abnormal intestinal transit time J:204737
abnormal synaptic transmission J:204737
impaired gastric peristalsis J:204737
Gusbmps/Gusbmps
KitW-41J/KitW-41J
B6(C)-KitW-41J Gusbmps/BrkJ 		abnormal lysosome morphology J:58272
decreased hematopoietic stem cell number J:58272
premature death J:58272
Il2rgtm1Cgn/Il2rgtm1Cgn
Kittm1.1Bsm/Kittm1.1Bsm
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 		arrested T cell differentiation J:90485
Il3tm1Glli/Il3tm1Glli
KitW/KitW-v
involves: 129S2/SvPas * C57BL/6 * WB 		increased susceptibility to parasitic infection J:80500
Kittm1(cre/ERT2)Dsa/Kit+
Prkg1tm2Naw/Prkg1tm2Naw
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 		abnormal gastrointestinal motility J:204737
abnormal intestinal peristalsis J:204737
abnormal intestinal transit time J:204737
Kittm1.1(cre)Jmol/Kittm2.1(cre/Esr1*)Jmol
Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh/Gt(ROSA)26Sor+
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * FVB 		abnormal heart development J:210584
neonatal lethality, complete penetrance J:210584
Kittm1.1(cre)Jmol/Kittm2.1(cre/Esr1*)Jmol
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J 		abnormal heart development J:210584
neonatal lethality, complete penetrance J:210584
Kittm1Rosay/Kit+
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal interstitial cell of Cajal morphology J:168676
hyperglycemia J:168676
obese J:168676
white spotting J:168676
KitW-19H/Kit+
B6.Cg-KitW-19H/EiJ 		constricted vagina orifice J:133405
normal reproductive system phenotype J:133405
KitW-19H/Kit+
involves: 101/H * C3H/HeH 		postnatal growth retardation J:7681
postnatal lethality, incomplete penetrance J:7681
variable body spotting J:7681
KitW-19H/Kit+
X/SryAKR/J
involves: AKR/J * C57BL/6J 		sex reversal J:133266
small testis J:133266
KitW-19H/KitW-19H
involves: 101/H * C3H/HeH 		embryonic lethality before implantation, complete penetrance J:7681
KitW-27H/Kit+
X/SryAKR/J
involves: AKR/J * C57BL/6J * CBA/H 		decreased testis weight J:133266
KitW-36H/KitW-bd
involves: 101/H * C3H/HeH * STOCK Rw Fgf5go Vps33abf 		absent coat pigmentation J:20782
KitW-42J/Kit+
X/SryAKR/J
involves: AKR/J * C57BL/6J 		small testis J:36829
true hermaphroditism J:36829
KitW-42J/Kit+
X/SryPOS-TIR
involves: C57BL/6J 		sex reversal J:36829
true hermaphroditism J:36829
KitW-42J/KitW-42J
X/SryAKR/J
involves: AKR/J * C57BL/6J 		abnormal internal male genitalia morphology J:36829
lethality throughout fetal growth and development, incomplete penetrance J:36829
KitW-57J/Kit+
involves: C58/J 		belly spot J:38382
KitW-57J/KitW-57J
involves: C58/J 		anemia J:38382
belly spot J:38382
head blaze J:38382
KitW-bd/Kit+
involves: STOCK Rw Fgf5go Vps33abf 		abnormal melanoblast morphology J:38382
belted J:14074
KitW-bd/KitW-bd
involves: STOCK Rw Fgf5go Vps33abf 		abnormal action potential J:45208
abnormal coat/hair pigmentation J:13934
abnormal melanoblast morphology J:38382
decreased Cajal-Retzius cell number J:45208
KitW-e/Kit+
X/SryAKR/J
involves: AKR/J * C57BL/6J 		decreased testis weight J:133266
KitW-sh/Kit+
involves: 101/H * C3H/HeH * CBA 		variable body spotting J:24351
KitW-sh/KitW-sh
B6.Cg-KitW-sh/HNihrJaeBsmGlliJ 		decreased susceptibility to induced hypothermia J:275367
decreased susceptibility to type I hypersensitivity reaction J:275367
KitW-sh/KitW-sh
involves: 101/H * C3H/HeH 		abnormal coat/hair pigmentation J:6857
abnormal definitive hematopoiesis J:6857
abnormal erythrocyte cell number J:6857
decreased erythrocyte cell number J:6857
decreased mast cell degranulation J:157470
decreased mast cell number J:145444
impaired behavioral response to xenobiotic J:157470
increased susceptibility to parasitic infection J:163761
KitW-sh/KitW-sh
involves: 101/H * C3H/HeH * CBA 		absent coat pigmentation J:24351
KitW-sh/KitW-sh
involves: C57BL/6J 		abnormal vascular permeability J:197334
decreased susceptibility to type I hypersensitivity reaction J:197334
KitW-sh/KitW-sh
Lyntm1Ard/Lyntm1Ard
involves: 101 * 129P2/OlaHsd * C3H/HeH 		abnormal circulating complement protein level J:161523
albuminuria J:161523
decreased B cell number J:161523
glomerulonephritis J:161523
increased anti-double stranded DNA antibody level J:161523
increased anti-nuclear antigen antibody level J:161523
increased basophil cell number J:161523
increased IgA level J:161523
increased IgE level J:161523
increased IgG2b level J:161523
increased IgM level J:161523
KitW-sh/KitW-v
involves: 101/H * C3H/HeH 		abnormal coat/hair pigmentation J:6857
abnormal definitive hematopoiesis J:6857
abnormal erythrocyte cell number J:6857
absent coat pigmentation J:6857
decreased erythrocyte cell number J:6857
macrocytic anemia J:6857
KitW-v/Kit+
Ph/Ph+
involves: C57BL 		abnormal coat/hair pigmentation J:125080
irregular coat pigmentation J:125080
KitW-v/Kit+
Rw/Rw+
involves: 101/H * C3H/HeH * C57BL 		abnormal coat/hair pigmentation J:125080
head spot J:125080
irregular coat pigmentation J:125080
KitW-v/Kit+
Snai2tm2Grid/Snai2+
involves: 129S1/Sv * C57BL 		variable body spotting J:80529
KitW-v/Kit+
Snai2tm2Grid/Snai2tm2Grid
involves: 129S1/Sv * C57BL 		variable body spotting J:80529
KitW-v/Kit+
Rps19Mhdadsk3/Rps19+
involves: C3HeB/FeJ * C57BL/6J 		belly spot J:139244
KitW-v/Kit+
Tg(Mt1-RET)304Ina/0
involves: BALB/c * C57BL/6 		decreased tumor incidence J:88074
decreased tumor-free survival time J:88074
increased melanoma incidence J:88074
KitW-v/Kit+
X/SryAKR/J
involves: AKR/J * C57BL/6J 		decreased testis weight J:133266
KitW-v/KitW-v
Ly6atm1Pmf/Ly6atm1Pmf
involves: 129P2/OlaHsd * C57BL/6 		abnormal common myeloid progenitor cell morphology J:81387
anemia J:81387
embryonic lethality, incomplete penetrance J:81387
KitW-v/KitW-v
Tg(Mt1-RET)304Ina/0
involves: BALB/c * C57BL/6 		abnormal melanogenesis J:88074
decreased tumor incidence J:88074
increased melanoma incidence J:88074
mosaic coat color J:88074
premature death J:88074
KitW-v/KitW-v
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6J * FVB/N 		abnormal ovary physiology J:236161
increased ovary tumor incidence J:236161
ovary cyst J:236161
KitW/Kit+
Tg(PGK1-KITLG*220)441Daw/0
involves: C3H/HeJ 		abnormal coat/hair pigmentation J:32600
decreased mast cell number J:32600
hypopigmentation J:32600
KitW/KitW
Tg(PDGFB-EPO)321Zbz/?
involves: C3H * C57BL/6 		abnormal B cell differentiation J:79128
abnormal T cell differentiation J:79128
decreased B cell number J:79128
decreased thymocyte number J:79128
KitWps/Kit+
Pax3Sp-1Wli/Pax3+
involves: C57BL/6J * CBA/CaJ 		belly spot J:196572
white spotting J:196572
Mitftm5.1Arnh/Mitftm5.1Arnh
Kittm1Alf/Kit+
involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N 		abnormal coat/hair pigmentation J:182722
abnormal hair follicle melanocyte morphology J:182722
abnormal melanocyte morphology J:182722
belly spot J:182722
Mitftm7.1Arnh/Mitftm7.1Arnh
Kittm1Alf/Kit+
involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N 		belly spot J:182722
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory