About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kras
Kirsten rat sarcoma viral oncogene homolog
MGI:96680
211 phenotypes from 15 alleles in 52 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Krasa/Krasa
multiple strains 		increased lung adenoma incidence J:17778, J:17850
Krasb/Krasb
multiple strains 		decreased lung tumor incidence J:17778, J:17850
Krastm1.1Khai/Kras+
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA/J 		abnormal hematopoietic system morphology/development J:276349
anemia J:276349
decreased hemoglobin content J:276349
enlarged spleen J:276349
increased leukocyte cell number J:276349
increased myeloid cell number J:276349
increased myeloid cell number in bone marrow J:276349
premature death J:276349
Krastm1.1Khai/Kras+
Tg(Fabp1-cre)1Jig/0
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N 		abnormal colon morphology J:276349
abnormal large intestine crypts of Lieberkuhn morphology J:276349
Krastm1.1Khai/Kras+
Tg(Pdx1-cre)6Tuv/0
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N 		normal neoplasm J:276349
Krastm1Bbd/Kras+
involves: 129S1/Sv * 129X1/SvJ 		decreased survivor rate J:172200
increased lung non-small cell carcinoma incidence J:172200
premature death J:172200
Krastm1Bbd/Kras+
Tg(CMV-cre)1Cgn/?
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 		abnormal cell proliferation J:86101
increased lung adenocarcinoma incidence J:86101
increased lung adenoma incidence J:86101
increased papilloma incidence J:86101
increased sarcoma incidence J:86101
premature death J:86101
prenatal lethality, incomplete penetrance J:86101
respiratory distress J:86101
Krastm1Bbd/Kras+
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 		increased prostate gland adenocarcinoma incidence J:143034
increased prostate intraepithelial neoplasia incidence J:143034
prostate gland hyperplasia J:143034
Krastm1Bbd/Kras+
Tg(CMV-cre/ERT)1Ipc/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal fibroblast proliferation J:86101
Harderian gland hyperplasia J:86101
increased lung adenocarcinoma incidence J:86101
increased lung adenoma incidence J:86101
premature death J:86101
respiratory distress J:86101
Krastm1Bbd/Kras+
Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd
involves: 129S1/Sv * 129X1/SvJ 		increased adenoma incidence J:161780
increased lung non-small cell carcinoma incidence J:161780
premature death J:161780
Krastm1Bbd/Krastm1Bbd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		embryonic lethality during organogenesis, complete penetrance J:86101
Krastm1Bbd/Krastm1Bbd
Tg(Cela1-tTA)#Eps/?
Tg(tetO-cre)3Jig/?
involves: 129S1/Sv * 129X1/SvJ * FVB/N 		increased pancreatic ductal adenocarcinoma incidence J:119988
increased tumor latency J:119988
Krastm1Bbd/Krastm2Bbd
Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd
involves: 129S1/Sv * 129X1/SvJ 		increased cell proliferation J:161780
increased lung non-small cell carcinoma incidence J:161780
increased lung tumor incidence J:161780
premature death J:161780
Krastm1Epa/Krastm1Epa
129P2/OlaHsd-Krastm1Epa 		no abnormal phenotype detected J:86863
Krastm1Epa/Krastm1Epa
involves: 129P2/OlaHsd * C57BL/6 		no abnormal phenotype detected J:86863
Krastm1Mok/Kras+
involves: 129S/SvEv * C57BL/6J 		no abnormal phenotype detected J:42943
Krastm1Mok/Krastm1Mok
involves: 129S/SvEv * C57BL/6J 		abnormal fetal cardiomyocyte proliferation J:42943
abnormal heart morphology J:42943
decreased embryo size J:42943
embryonic growth retardation J:42943
normal hematopoietic system phenotype J:42943
increased neuron apoptosis J:42943
normal liver/biliary system phenotype J:42943
prenatal lethality, complete penetrance J:42943
small heart J:42943
thin myocardium J:42943
thin ventricular wall J:42943
Krastm1Tyj/Krastm1Tyj
involves: 129S2/SvPas 		abnormal definitive hematopoiesis J:43433
anemia J:43433
decreased embryo size J:43433
fetal growth retardation J:43433
increased apoptosis J:43433
liver hypoplasia J:43433
pale liver J:43433
pallor J:43433
pericardial edema J:43433
prenatal lethality, complete penetrance J:43433
small liver J:43433
Krastm2Tyj/Kras+
involves: 129S2/SvPas 		abnormal bronchus morphology J:136369
increased carcinoma incidence J:129627
increased fibrosarcoma incidence J:129627
increased hemangiosarcoma incidence J:129627
increased lung adenocarcinoma incidence J:136369
increased lymphoma incidence J:129627
increased mesothelioma incidence J:129627
increased papilloma incidence J:129627
increased sarcoma incidence J:129627
increased skin papilloma incidence J:68981
increased squamous cell carcinoma incidence J:129627
increased T cell derived lymphoma incidence J:68981
increased tumor incidence J:129627
premature death J:68981, J:129627
Krastm2Tyj/Kras+
involves: 129S2/SvPas * C57BL/6 		abnormal large intestine crypts of Lieberkuhn morphology J:68981
increased lung adenocarcinoma incidence J:68981
increased lung adenoma incidence J:68981
increased lung tumor incidence J:68981
increased skin papilloma incidence J:68981
increased T cell derived lymphoma incidence J:68981
increased tumor incidence J:68981
premature death J:68981
Krastm3Bbd/Krastm3Bbd
B6.129-Krastm3Bbd 		embryonic lethality, complete penetrance J:101977
Krastm3Tyj/Kras+
involves: 129S4/SvJae 		increased lung tumor incidence J:119477
increased skin papilloma incidence J:68981
increased T cell derived lymphoma incidence J:68981
premature death J:68981
Krastm3Tyj/Kras+
involves: 129S4/SvJae * C57BL/6 		abnormal large intestine crypts of Lieberkuhn morphology J:68981
increased lung adenocarcinoma incidence J:68981
increased lung adenoma incidence J:68981
increased lung tumor incidence J:68981
increased skin papilloma incidence J:68981
increased T cell derived lymphoma incidence J:68981
increased tumor incidence J:68981
premature death J:68981
Krastm3Tyj/Krastm3Tyj
involves: 129S4/SvJae 		increased lung tumor incidence J:237900
increased skin papilloma incidence J:237900
increased T cell derived lymphoma incidence J:237900
premature death J:237900
Krastm4.1Bbd/Kras+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N 		enlarged spleen J:223433
premature death J:223433
Krastm4.1Bbd/Krastm4.1Bbd
129S2.129(Cg)-Krastm4.1Bbd 		perinatal lethality, incomplete penetrance J:223433
Krastm4.1Bbd/Krastm4.1Bbd
B6J.129(FVB)-Krastm4.1Bbd 		perinatal lethality, complete penetrance J:223433
Krastm4.1Bbd/Krastm4.1Bbd
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N 		abnormal bone marrow cell physiology J:223433
abnormal common lymphocyte progenitor cell morphology J:223433
abnormal common myeloid progenitor cell morphology J:223433
abnormal cranium morphology J:223433
abnormal ear position J:223433
abnormal facial morphology J:223433
abnormal heart morphology J:223433
abnormal hematopoietic system morphology/development J:223433
abnormal kidney morphology J:223433
abnormal myocardial fiber physiology J:223433
anemia J:223433
cellular necrosis J:223433
decreased body length J:223433
decreased body size J:223433
decreased CD8-positive, alpha-beta T cell number J:223433
decreased cranium length J:223433
enlarged spleen J:223433
extramedullary hematopoiesis J:223433
flattened snout J:223433
heart hyperplasia J:223433
increased basophil cell number J:223433
increased cardiac muscle contractility J:223433
increased cardiac output J:223433
increased cell proliferation J:223433
increased cranium height J:223433
increased cranium width J:223433
increased eosinophil cell number J:223433
increased granulocyte monocyte progenitor cell number J:223433
increased hematopoietic stem cell number J:223433
increased leukocyte cell number J:223433
increased myeloid cell number J:223433
increased myocardial fiber number J:223433
increased neutrophil cell number J:223433
ocular hypertelorism J:223433
perinatal lethality, incomplete penetrance J:223433
premature death J:223433
slow postnatal weight gain J:223433
spleen vascular congestion J:223433
thick aortic valve J:223433
thrombocytopenia J:223433
triangular face J:223433
Krastm4.1Tyj/Kras+
Not Specified 		abnormal brain development J:89333
abnormal embryonic neuroepithelium morphology J:89333
decreased embryo size J:89333
embryonic lethality during organogenesis, complete penetrance J:89333
enlarged heart J:89333
increased embryonic neuroepithelium apoptosis J:89333
pallor J:89333
Krastm4Tyj/Kras+
B6.129S4-Krastm4Tyj 		increased lung adenocarcinoma incidence J:177379
increased lung adenoma incidence J:177379
premature death J:177379
Krastm4Tyj/Kras+
either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C3H/HeJ) 		abnormal ovary morphology J:96296
abnormal peritoneum morphology J:96296
Krastm4Tyj/Kras+
involves: 129S4/SvJae 		decreased tumor-free survival time J:333347
increased lung adenocarcinoma incidence J:207982, J:333347
increased lung adenoma incidence J:207982, J:333347
increased lung tumor incidence J:119477, J:216266, J:299900
Krastm4Tyj/Kras+
involves: 129S4/SvJae 		abnormal bronchiole morphology J:147590
abnormal tumor morphology J:147590
bronchiolar epithelial hyperplasia J:147590
decreased tumor growth/size J:147590
increased lung adenocarcinoma incidence J:147590
increased lung adenoma incidence J:158937
increased lung carcinoma incidence J:158937
increased lung tumor incidence J:147590, J:158937
increased regulatory T cell number J:154046
lung epithelium hyperplasia J:158937
premature death J:147590
thick pulmonary interalveolar septum J:147590
uterus adenomyosis J:154046
Krastm4Tyj/Kras+
involves: 129S4/SvJae * C57BL/6 		increased lung adenoma incidence J:203686
Krastm4Tyj/Kras+
involves: 129S4/SvJae * C57BL/6 * FVB/N 		increased lung adenocarcinoma incidence J:124682
premature death J:124682
Krastm4Tyj/Kras+
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJae 		increased lung tumor incidence J:158937
increased lung weight J:158937
postnatal lethality, complete penetrance J:158937
Krastm4Tyj/Kras+
Tg(Tek-cre)12Flv/0
involves: 129S4/SvJae * C3H * C57BL/6 		normal embryo phenotype J:119477
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA 		abnormal definitive hematopoiesis J:88163
abnormal erythrocyte morphology J:88163
abnormal hepatobiliary system morphology J:88163
abnormal myelopoiesis J:88163
anemia J:88163
cachexia J:88163
decreased hematocrit J:88163
enlarged spleen J:88163
extramedullary hematopoiesis J:88163
increased esophageal papilloma incidence J:88163
increased granulocyte number J:88163
increased leukocyte cell number J:88163
increased lung adenoma incidence J:88163
increased lymphoblastic lymphoma incidence J:88163
increased oral papilloma incidence J:88163
increased papilloma incidence J:88163
increased skin papilloma incidence J:88163
increased spleen red pulp amount J:88163
lymphoid hyperplasia J:88163
myeloid hyperplasia J:88163
premature death J:88163
ruffled hair J:88163
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA/J 		abnormal hematopoietic system morphology/development J:276349
anemia J:276349
enlarged spleen J:276349
increased myeloid cell number J:276349
increased myeloid cell number in bone marrow J:276349
premature death J:276349
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA 		abnormal erythropoiesis J:87429, J:115071
abnormal myelopoiesis J:87429
anemia J:87429, J:115071
anisopoikilocytosis J:115071
decreased mean corpuscular hemoglobin J:115071
enlarged liver J:87429
enlarged spleen J:87429, J:115071
increased circulating erythropoietin level J:115071
increased leukocyte cell number J:87429
increased monocyte cell number J:87429
increased splenocyte proliferation J:87429
myeloid hyperplasia J:87429
polychromatophilia J:115071
premature death J:87429
reticulocytosis J:115071
Krastm4Tyj/Kras+
Tg(MMTV-cre)4Mam/0
involves: 129S4/SvJae * FVB 		submandibular gland hyperplasia J:89333
Krastm4Tyj/Kras+
Meox2tm1(cre)Sor/Meox2+
involves: 129S4/SvJae * 129S4/SvJaeSor 		abnormal atrioventricular valve morphology J:119477
abnormal branching involved in lung morphogenesis J:119477
abnormal bronchus morphology J:119477
abnormal cardiovascular system physiology J:119477
abnormal embryonic erythrocyte morphology J:119477
abnormal embryonic erythropoiesis J:119477
conotruncal ridge hyperplasia J:119477
dilated respiratory conducting tube J:119477
double outlet right ventricle J:119477
edema J:119477
normal embryo phenotype J:119477
embryonic lethality during organogenesis, incomplete penetrance J:119477
hemorrhage J:119477
impaired branching involved in bronchus morphogenesis J:119477
impaired branching involved in terminal bronchiole morphogenesis J:119477
increased hepatocyte apoptosis J:119477
lethality throughout fetal growth and development, complete penetrance J:119477
liver hypoplasia J:119477
pallor J:119477
ventricular septal defect J:119477
Krastm4Tyj/Kras+
Tg(Prm-cre)58Og/0
involves: 129S4/SvJae 		abnormal placenta labyrinth morphology J:119477
abnormal placental labyrinth vasculature morphology J:119477
absent vitelline blood vessels J:119477
embryonic growth arrest J:119477
embryonic lethality during organogenesis, complete penetrance J:119477
increased embryonic tissue cell apoptosis J:119477
pale yolk sac J:119477
Krastm4Tyj/Kras+
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S4/SvJae * C57BL/6 * DBA 		increased cholangiocarcinoma incidence J:184949
increased liver tumor incidence J:254370
Krastm4Tyj/Kras+
Ptf1atm1.1(cre)Cvw/Ptf1a+
B6.129(Cg)-Krastm4Tyj Ptf1atm1.1(cre)Cvw 		increased metastatic potential J:138959
increased pancreas tumor incidence J:138959
increased pancreas weight J:138959
increased pancreatic ductal adenocarcinoma incidence J:138959
increased pancreatic intraepithelial neoplasia incidence J:138959
Krastm4Tyj/Kras+
Ptf1atm1.1(cre)Cvw/Ptf1a+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		abnormal pancreatic acinar cell morphology J:262746
enlarged pancreas J:87973
increased pancreatic ductal adenocarcinoma incidence J:87973, J:116130
increased pancreatic intraepithelial neoplasia incidence J:262746
increased tumor incidence J:87973
Krastm4Tyj/Kras+
Ptf1atm1.1(cre)Cvw/Ptf1a+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 		increased pancreatic intraepithelial neoplasia incidence J:116129
Krastm4Tyj/Kras+
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0
involves: 129/Sv * C57BL/6 		abnormal branching involved in lung morphogenesis J:119477
abnormal bronchus epithelium morphology J:119477
abnormal lung epithelium morphology J:119477
postnatal lethality, complete penetrance J:119477
Krastm4Tyj/Kras+
Tg(KRT14-cre/ERT)20Efu/0
involves: 129S4/SvJae * C57BL/6 * CD-1 * FVB/N 		increased mouth tumor incidence J:210533
Krastm4Tyj/Kras+
Tg(Fabp1-cre)1Jig/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N 		abnormal intestinal epithelium morphology J:132357
abnormal intestinal goblet cell morphology J:132357
abnormal large intestine crypts of Lieberkuhn morphology J:132357
Krastm4Tyj/Kras+
Tg(Fabp1-cre)1Jig/0
involves: 129S4/SvJae * C57BL/6 * FVB/N 		abnormal colon morphology J:276349
abnormal large intestine crypts of Lieberkuhn morphology J:276349
absent Paneth cells J:276349
Krastm4Tyj/Kras+
Tg(Fabp1-cre)1Jig/0
involves: 129S4/SvJae * FVB/N 		abnormal colon morphology J:89333
Krastm4Tyj/Kras+
Tg(KRT5-cre/PGR)1Der/?
involves: 129/Sv * C57BL/6 * FVB * ICR 		increased skin papilloma incidence J:124222
Krastm4Tyj/Kras+
Tg(Pdx1-cre)89.1Dam/0
involves: 129S4/SvJae * C57BL/6 * CBA 		ascites J:164210
distended abdomen J:164210
enlarged pancreatic islets J:87196
increased pancreatic ductal adenocarcinoma incidence J:116130, J:164210
increased pancreatic intraepithelial neoplasia incidence J:87196, J:164210
pancreatic acinar-to-ductal metaplasia J:164210
Krastm4Tyj/Kras+
Tg(Pdx1-cre)89.1Dam/0
involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N 		increased metastatic potential J:108298
increased pancreas tumor incidence J:108298
Krastm4Tyj/Kras+
Tg(Pdx1-cre)6Tuv/0
involves: 129S4/SvJae * C57BL/6 * FVB/N 		abnormal pancreatic duct morphology J:214846
increased pancreatic intraepithelial neoplasia incidence J:98936, J:214846, J:276349
Krastm4Tyj/Kras+
Tg(Pdx1-cre)6Tuv/?
involves: 129S4/SvJae * FVB/N 		enlarged pancreas J:87973
increased pancreatic ductal adenocarcinoma incidence J:87973
Krastm4Tyj/Kras+
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129S4/SvJae * 129S6/SvEvTac 		normal integument phenotype J:172048
Krastm4Tyj/Kras+
Tg(Krt1-15-cre/PGR*)22Cot/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL/J 		increased papilloma incidence J:203922
Krastm4Tyj/Kras+
Tg(Krt1-15-cre/PGR*)22Cot/0
involves: 129S4/SvJae * C57BL/6J * SJL/J 		increased facial tumor incidence J:172048
increased lip tumor incidence J:172048
increased skin papilloma incidence J:172048
increased skin tumor incidence J:172048
Krastm4Tyj/Kras+
Tg(Upk2-cre)6Xrw/0
involves: 129S4/SvJae * FVB/N 		normal neoplasm J:174242, J:234236
normal renal/urinary system phenotype J:234236
Krastm4Tyj/Kras+
Tg(Scgb1a1-cre)1Kkw/?
involves: 129 * C57BL/6 * FVB/N 		increased inflammatory response J:107260
increased lung adenocarcinoma incidence J:107260
premature death J:107260
Krastm4Tyj/Kras+
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129S4/SvJae * FVB 		abnormal melanocyte morphology J:164588
hyperpigmentation J:164588
increased melanoma incidence J:164588
Krastm4Tyj/Kras+
Tg(TPO-cre)1Shk/0
129.Cg-Krastm4Tyj Tg(Tpo-cre)1Shk 		normal endocrine/exocrine gland phenotype J:147732
Krastm4Tyj/Kras+
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
involves: 129S4/SvJae 		abnormal colon goblet cell morphology J:132357
abnormal intestinal epithelium morphology J:132357
abnormal large intestine crypts of Lieberkuhn morphology J:132357
Krastm4Tyj/Kras+
Tg(Pbsn-cre)20Fwan/0
involves: 129S4/SvJae * FVB/NCrl 		abnormal intestine morphology J:178461
abnormal prostate gland physiology J:178461
increased prostate intraepithelial neoplasia incidence J:178461
prostate gland hyperplasia J:178461
Krastm4Tyj/Kras+
Krt19tm1(cre/ERT)Ggu/Krt19+
involves: 129S4/SvJae * 129S6/SvEvTac 		abnormal skin sebaceous gland morphology J:172048
enlarged sebaceous gland J:172048
increased cell proliferation J:172048
increased hair follicle cell proliferation J:172048
increased lip tumor incidence J:172048
increased skin papilloma incidence J:172048
increased skin tumor incidence J:172048
sebaceous gland hyperplasia J:172048
Krastm4Tyj/Kras+
Scgb1a1tm1.1(cre)Fjd/Scgb1a1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		abnormal lung morphology J:131721
increased lung adenoma incidence J:131721
increased lung tumor incidence J:131721
premature death J:131721
Krastm4Tyj/Kras+
Tg(Fabp7-cre,-lacZ)3Gtm/0
involves: 129S4/SvJae * C57BL/6 * CBA 		abnormal astrocyte morphology J:139866
abnormal brain development J:139866
abnormal CNS glial cell morphology J:139866
abnormal hippocampus morphology J:139866
normal endocrine/exocrine gland phenotype J:138868
normal growth/size/body region phenotype J:138868, J:139866
normal mortality/aging J:139866
normal nervous system phenotype J:139866
Krastm4Tyj/Kras+
Tg(Cela1-cre/ERT)1Dam/0
involves: 129S4/SvJae 		increased lung non-small cell carcinoma incidence J:197054
increased pancreas tumor incidence J:197054
Krastm4Tyj/Kras+
Tg(Gfap-cre)77.6Mvs/0
involves: 129 * BALB/c * C57BL/6NHsd 		normal neoplasm J:154673
Krastm4Tyj/Kras+
Tg(Cdh5-cre/ERT2)1Rha/0
involves: 129S4/SvJae * FVB 		abnormal brain vasculature morphology J:312482
arteriovenous malformation J:312482
intracranial hemorrhage J:312482
postnatal lethality, incomplete penetrance J:312482
Krastm4Tyj/Kras+
Tg(IVL-cre/ERT2)1Blpn/0
involves: 129S4/SvJae * C57BL/6 		epidermal hyperplasia J:172048
increased facial tumor incidence J:172048
increased lip tumor incidence J:172048
increased skin papilloma incidence J:172048
increased skin tumor incidence J:172048
thick epidermis J:172048
Krastm4Tyj/Kras+
Tg(Slco1c1-icre/ERT2)1Mash/0
involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB 		abnormal brain vasculature morphology J:312482
arteriovenous malformation J:312482
intracranial hemorrhage J:312482
Krastm4Tyj/Kras+
Sftpctm1.1(cre/ERT2)Ptch/Sftpc+
involves: 129P2/OlaHsd * C57BL/6 * FVB 		increased lung adenoma incidence J:195738
Krastm4Tyj/Kras+
Tg(Tg-cre/ERT2)#Mmcm/0
involves: 129S4/SvJae * FVB/NCr 		normal endocrine/exocrine gland phenotype J:172205
Krastm4Tyj/Krastm4Tyj
B6.129S4-Krastm4Tyj 		increased cell proliferation J:187371
Krastm4Tyj/Krastm4Tyj
Bhlha15tm3(cre/ERT2)Skz/Bhlha15+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		increased pancreatic intraepithelial neoplasia incidence J:142189
Krastm4Tyj/Krastm4Tyj
Ptf1atm1(cre)Hnak/Ptf1a+
involves: 129S4/SvJae 		increased pancreatic intraepithelial neoplasia incidence J:162125
Krastm4Tyj/Krastm4Tyj
Tg(Cela1-cre/ERT2)1Stof/0
involves: 129S4/SvJae * C57BL/6 * SJL 		increased pancreatic intraepithelial neoplasia incidence J:142189
Krastm4Tyj/Krastm4Tyj
Tg(Cela1-cre/ERT)1Dam/0
involves: 129S4/SvJae 		increased pancreatic intraepithelial neoplasia incidence J:142188
Krastm4Tyj/Krastm4Tyj
Tg(Pdx1-cre)89.1Dam/0
involves: 129S4/SvJae * C57BL/6 * DBA/2 		increased pancreatic intraepithelial neoplasia incidence J:151781
pancreas cyst J:151781
Krastm4Tyj/Krastm4Tyj
Tg(Pdx1-cre/Esr1*)35.10Dam/0
involves: 129S4/SvJae * C57BL/6 * CBA 		increased pancreatic intraepithelial neoplasia incidence J:142188
Krastm4Tyj/Krastm4Tyj
Tg(Pdx1-cre/Esr1*)35.10Dam/0
involves: 129S4/SvJae * C57BL/6 * SJL 		normal neoplasm J:142189
Krastm5Tyj/Kras+
involves: 129S4/SvJae * C57BL/6 		increased lung tumor incidence J:172206
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory