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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kdr
kinase insert domain protein receptor
MGI:96683
57 phenotypes from 13 alleles in 16 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Kdrorv/Kdrorv
involves: 129S1/Sv * C57BL/6 * FVB/NJ 		abnormal cranial neural crest cell migration J:171522
abnormal mandibular prominence morphology J:171522
abnormal nervous system development J:171522
abnormal second pharyngeal arch morphology J:171522
abnormal trigeminal ganglion morphology J:171522
abnormal vasculogenesis J:171522
absent fourth pharyngeal arch J:171522
absent third pharyngeal arch J:171522
decreased embryo size J:171522
embryonic lethality during organogenesis, complete penetrance J:171522
failure of chorioallantoic fusion J:171522
impaired cranial neural crest cell differentiation J:171522
Kdrtm1.1Eia/Kdrtm1.1Eia
B6.129P2-Kdrtm1.1Eia 		abnormal vascular development J:156869
embryonic lethality, complete penetrance J:156869
Kdrtm1.1Jamb/Kdrtm1.1Jamb
involves: 129S1/Sv * 129X1/SvJ * ICR 		abnormal lymphangiogenesis J:154336
increased susceptibility to injury J:154336
lymphatic vessel hyperplasia J:154336
Kdrtm1.1Jamb/Kdrtm1.1Jamb
Tg(KRT14-cre)1Efu/0
involves: 129S1/Sv * 129X1/SvJ * ICR 		lymphatic vessel hyperplasia J:154336
Kdrtm1.1Jamb/Kdrtm1.1Jamb
Tg(Pax6-cre,GFP)1Pgr/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR 		abnormal basement membrane morphology J:154336
abnormal cornea morphology J:154336
abnormal lymphatic vessel morphology J:154336
lymphatic vessel hyperplasia J:154336
Kdrtm1.1Msh/Kdrtm1.1Msh
involves: 129P2/OlaHsd * C57BL/6J 		absent organized vascular network J:96124
absent vitelline blood vessels J:96124
embryonic lethality during organogenesis, complete penetrance J:96124
impaired hematopoiesis J:96124
Kdrtm1.1Vlcg/Kdrtm1.1Vlcg
involves: 129S6/SvEvTac * C57BL/6NTac 		no abnormal phenotype detected J:200671
Kdrtm1.2Jamb/Kdrtm1.2Jamb
involves: 129S1/Sv * 129X1/SvJ * ICR 		abnormal embryo development J:154336
Kdrtm1Eze/Kdrtm1Eze
Tg(Prrx1-cre)1Cjt/0
involves: C57BL/6J * SJL/J 		normal cardiovascular system phenotype J:147285
Kdrtm1Jrt/Kdr+
involves: 129S1/Sv * 129X1/SvJ 		no abnormal phenotype detected J:26846
Kdrtm1Jrt/Kdr+
Tg(tetO-Kdr*)4377.5Rwng/0
Tg(Cebpb-tTA)5Bjd/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N * NMRI 		abnormal liver development J:100427
Kdrtm1Jrt/Kdrtm1.1Jamb
Tg(CAG-cre/Esr1*)1Egwa/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 		abnormal induced retina neovascularization J:173943
Kdrtm1Jrt/Kdrtm1.1Msh
involves: 129P2/OlaHsd * B6.129-Kdrtm1Jrt/J * C57BL/6J 		abnormal dorsal aorta morphology J:96124
abnormal extraembryonic mesoderm development J:96124
absent organized vascular network J:96124
absent visceral yolk sac blood islands J:96124
Kdrtm1Jrt/Kdrtm1Jrt
B6.129-Kdrtm1Jrt/J 		abnormal dorsal aorta morphology J:96124
abnormal extraembryonic mesoderm development J:96124
absent organized vascular network J:96124
absent visceral yolk sac blood islands J:96124
absent vitelline blood vessels J:96124
impaired hematopoiesis J:96124
Kdrtm1Jrt/Kdrtm1Jrt
involves: 129S1/Sv * 129X1/SvJ 		abnormal allantois morphology J:125783
abnormal definitive hematopoiesis J:26846
abnormal embryonic tissue morphology J:26846
absent organized vascular network J:26846
absent visceral yolk sac blood islands J:26846
absent vitelline blood vessels J:26846
congestive heart failure J:26846
decreased embryo size J:26846
embryo tissue necrosis J:26846
embryonic lethality during organogenesis, complete penetrance J:26846
Kdrtm1Jrt/Kdrtm1Jrt
Not Specified 		absent organized vascular network J:95387
Kdrtm1Jrt/Kdrtm2Sato
Tg(Nes-cre)1Wmz/0
involves: 129S1/Sv * 129X1/SvJ 		normal nervous system phenotype J:175836
Kdrtm1Wag/Kdrtm1Wag
Nfatc1tm1.1(cre)Bz/Nfatc1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal angiogenesis J:193198
abnormal coronary artery morphology J:193198
abnormal interventricular septum morphology J:193198
decreased body size J:193198
heart hemorrhage J:193198
lethality throughout fetal growth and development, complete penetrance J:193198
Kdrtm1Wag/Kdrtm1Wag
Tg(Nes-cre)1Kln/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		normal behavior/neurological phenotype J:86207
normal nervous system phenotype J:86207
Kdrtm2.1Jrt/Kdrtm2.1Jrt
Tg(Cdh5-cre/ERT2)#Ykub/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal retina vasculature morphology J:217533
decreased total retina thickness J:217533
thin retina inner plexiform layer J:217533
Kdrtm2.1Jrt/Kdrtm2.1Jrt
Tg(Pax6-cre,GFP)2Pgr/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal retina vasculature morphology J:217533
persistence of hyaloid vascular system J:217533
normal vision/eye phenotype J:217533
Kdrtm2.1Msh/Kdrtm2.1Msh
involves: 129P2/OlaHsd * C57BL/6J 		no abnormal phenotype detected J:96124
Tg(tetO-Kdr*)4377.5Rwng/0
Tg(Cebpb-tTA)5Bjd/0
involves: FVB/N * NMRI 		abnormal blood vessel morphology J:100427
abnormal hepatocyte morphology J:100427
abnormal liver morphology J:100427
abnormal liver physiology J:100427
normal homeostasis/metabolism phenotype J:100427
jaundice J:100427
normal liver/biliary system phenotype J:100427
perinatal lethality, incomplete penetrance J:100427
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10/29/2024
MGI 6.24 		The Jackson Laboratory