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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kdr
kinase insert domain protein receptor
MGI:96683
48 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Angpt1tm1.2Seq/Angpt1tm1.2Seq
Kdrtm2.1Jrt/Kdr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal brain vasculature morphology J:174022
abnormal heart development J:174022
abnormal vascular development J:174022
decreased embryo size J:174022
embryonic lethality during organogenesis, complete penetrance J:174022
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Kdrtm1(cre)Sato/Kdr+
involves: 129S1/Sv * 129S7/SvEvBrd 		abnormal vascular branching morphogenesis J:112269
abnormal vascular development J:112269
abnormal vein morphology J:112269
abnormal visceral yolk sac morphology J:112269
abnormal vitelline vasculature morphology J:112269
absent atrioventricular cushions J:112269
decreased embryo size J:112269
embryonic growth arrest J:112269
embryonic lethality during organogenesis, complete penetrance J:112269
normal hematopoietic system phenotype J:112269
hemorrhage J:112269
internal hemorrhage J:112269
pale yolk sac J:112269
pallor J:112269
pericardial effusion J:112269
small heart J:112269
vascular smooth muscle hypoplasia J:112269
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Kdrtm1(cre)Sato/Kdr+
involves: 129S1/Sv * 129X1/SvJ 		abnormal blood-brain barrier function J:142352
abnormal vasculogenesis J:142352
embryonic lethality during organogenesis, complete penetrance J:142352
intracranial hemorrhage J:142352
spinal hemorrhage J:142352
Dnm1tm2.1Pdc/Dnm1tm2.1Pdc
Dnm2tm1.1Pdc/Dnm2tm1.1Pdc
Kdrtm2.1Jrt/Kdrtm2.1Jrt
Tg(Pax6-cre,GFP)2Pgr/0
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6 		abnormal retina vasculature morphology J:217533
Flt1tm1.1Fong/Flt1tm1.1Fong
Kdrtm1Jrt/Kdr+
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
involves: 129 * C57BL/6NCr * CD-1 		increased angiogenesis J:202202
Flt1tm2Msh/Flt1tm2Msh
Kdrtm1Jrt/Kdr+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal vascular endothelial cell differentiation J:95387
abnormal vascular endothelial cell migration J:95387
prenatal lethality, incomplete penetrance J:95387
Flt1tm2Msh/Flt1tm2Msh
Kdrtm1Jrt/Kdrtm1Jrt
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal vascular endothelial cell migration J:95387
prenatal lethality J:95387
Gt(ROSA)26Sortm1(Vegfa*)Jhai/Gt(ROSA)26Sor+
Kdrtm1Wag/Kdrtm1Wag
Tg(Col2a1-cre)1Bhr/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL 		abnormal blood vessel morphology J:156474
abnormal bone structure J:156474
abnormal long bone diaphysis morphology J:156474
abnormal skeleton development J:156474
increased bone mass J:156474
normal skeleton phenotype J:156474
Gt(ROSA)26Sortm1(Wnk1)Clhu/Gt(ROSA)26Sor+
Kdrtm1(cre)Sato/Kdr+
Wnk1Gt(OST38262)Lex/Wnk1Gt(OST38262)Lex
involves: 129S1/Sv * 129S5/SvEvBrd 		abnormal embryo development J:152906
normal cardiovascular system phenotype J:152906
Kdrtm1.1Eia/Kdr+
Nrp2tm1Ddg/Nrp2+
involves: 129P2/OlaHsd * C57BL/6 		normal cardiovascular system phenotype J:156869
Kdrtm1Jrt/Kdr+
Ptentm1Hwu/Ptentm1Hwu
Twist2tm1.1(cre)Dor/Twist2+
B6.129-Twist2tm1.1(cre)Dor Kdrtm1Jrt Ptentm1Hwu 		abnormal lung morphology J:192736
abnormal vasculogenesis J:192736
Kdrtm1Jrt/Kdr+
Prdm1tm2Rob/Prdm1tm2Rob
involves: 129 		abnormal placental labyrinth vasculature morphology J:187742
Kdrtm1Jrt/Kdr+
Tmem204tm1.1Ali/Tmem204tm1.1Ali
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 		abnormal lymphatic vessel smooth muscle morphology J:159519
enlarged lymphatic vessel J:159519
Kdrtm1Jrt/Kdr+
Rasip1tm1.1Oncl/Rasip1tm1.1Oncl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal vasculogenesis J:174152
abnormal vitelline vascular remodeling J:174152
Kdrtm1Wag/Kdrtm1Wag
Nfatc1tm1.1(cre)Bz/Nfatc1+
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 		abnormal angiogenesis J:193198
abnormal coronary artery morphology J:193198
Kdrtm1Ykub/Kdrtm1Ykub
Not Specified 		enlarged lymphatic vessel J:217533
lymphatic vessel hyperplasia J:217533
Kdrtm1Ykub/Kdrtm2.1Jrt
Tg(Pax6-cre,GFP)2Pgr/0
involves: 129S1/Sv * 129X1/SvJ 		normal cardiovascular system phenotype J:217533
normal vision/eye phenotype J:217533
Kdrtm2Sato/Kdrtm2Sato
Vegfatm2Gne/Vegfatm2Gne
Tg(Pax6-cre,GFP)2Pgr/0
involves: 129S1/Sv 		abnormal retina vasculature morphology J:217533
Smad4tm2.1Cxd/Smad4tm2.1Cxd
Kdrtm1(cre)Sato/Kdr+
involves: 129S1/Sv * 129S6/SvEvTac 		abnormal embryonic hematopoiesis J:112269
abnormal trabecula carnea morphology J:112269
abnormal vitelline vasculature morphology J:112269
absent atrioventricular cushions J:112269
embryonic lethality during organogenesis, complete penetrance J:112269
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory