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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Krt10
keratin 10
MGI:96685
37 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Krt10M1Btlr/?
C57BL/6J-Krt10M1Btlr 		waved hair J:147340
Krt10tm1Der/Krt10+
Tg(KRT14-cre/PGR)1Der/0
involves: 129S7/SvEvBrd * C57BL/6 * FVB * ICR 		blistering J:82300
hyperkeratosis J:82300
scaly skin J:82300
Krt10tm1Der/Krt10tm1Der
Tg(KRT14-cre/PGR)1Der/0
involves: 129S7/SvEvBrd * C57BL/6 * FVB * ICR 		abnormal epidermis stratum spinosum morphology J:82300
blistering J:82300
neonatal lethality, complete penetrance J:82300
skin lesions J:82300
Krt10tm1Tmm/Krt10+
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6) 		abnormal autopod morphology J:31853
abnormal epidermis stratum granulosum morphology J:31853
abnormal epidermis stratum spinosum morphology J:31853
abnormal epidermis suprabasal layer morphology J:31853
abnormal foot pad morphology J:31853
abnormal skin morphology J:31853
abnormal tail morphology J:31853
decreased body weight J:31853
flaky skin J:31853
hyperkeratosis J:31853
increased susceptibility to infection J:31853
reddish skin J:31853
scaly ears J:31853
scaly skin J:31853
Krt10tm1Tmm/Krt10tm1Tmm
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6) 		abnormal epidermis stratum basale morphology J:31853
abnormal epidermis stratum corneum morphology J:31853
abnormal epidermis stratum granulosum morphology J:31853
abnormal epidermis stratum spinosum morphology J:31853
abnormal epidermis suprabasal layer morphology J:31853
abnormal skin morphology J:31853
acanthosis J:31853
blistering J:31853
decreased skin tensile strength J:31853
hyperkeratosis J:31853
neonatal lethality, complete penetrance J:31853
reddish skin J:31853
translucent skin J:31853
Krt10tm2Tmm/Krt10tm2Tmm
involves: 129P2/OlaHsd * BALB/c 		abnormal epidermal layer morphology J:93045, J:93249
abnormal epidermis stratum corneum morphology J:93249, J:102127
abnormal epidermis stratum granulosum morphology J:93249
abnormal epidermis suprabasal layer morphology J:93045
abnormal sebaceous lipid secretion J:102127
abnormal sebocyte differentiation J:102127
abnormal sebocyte morphology J:102127
abnormal stratum corneum lipid matrix formation J:102127
decreased incidence of induced tumors J:93045
enlarged sebaceous gland J:102127
greasy coat J:102127
increased keratohyalin granule size J:93249
increased sebocyte proliferation J:102127
increased sebum secretion J:102127
ruffled hair J:102127
Krt10tm2Tmm/Krt10tm2Tmm
involves: 129P2/OlaHsd * BALB/c * C57BL/6N 		abnormal epidermis suprabasal layer morphology J:214772
epidermal hyperplasia J:214772
hypergranulosis J:214772
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory