Krt2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Krt2
keratin 2
MGI:96699

25 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Krt2^Mhdadsk2/Krt2⁺ C3HeB/FeJ-Krt2^Mhdadsk2/Ieg	abnormal skin pigmentation	J:81301
	increased ear pigmentation	J:81301
	increased foot pad pigmentation	J:81301
	increased tail pigmentation	J:81301
	scaly skin	J:81301
	thick epidermis	J:81301
Krt2^Mhdadsk2/Krt2^Mhdadsk2 involves: C3HeB/FeJ * C57BL/6J	abnormal skin pigmentation	J:81301
	increased ear pigmentation	J:81301
	increased foot pad pigmentation	J:81301
	increased tail pigmentation	J:81301
	scaly skin	J:81301
	thick epidermis	J:81301
Krt2^{tm1a(KOMP)Wtsi}/Krt2^{tm1a(KOMP)Wtsi} involves: 129P2/OlaHsd * BALB/c * C57BL/6N	abnormal epidermis suprabasal layer morphology	J:214772
	epidermal hyperplasia	J:214772
	hypergranulosis	J:214772
Krt2^{tm1a(KOMP)Wtsi}/Krt2^{tm1a(KOMP)Wtsi} involves: C57BL/6N	abnormal corneocyte morphology	J:214772
	abnormal epidermis suprabasal layer morphology	J:214772
	abnormal keratinocyte differentiation	J:214772
	acanthosis	J:214772
	hypergranulosis	J:214772
	hyperkeratosis	J:214772
	impaired skin barrier function	J:214772
	increased ear pigmentation	J:214772
	increased keratinocyte proliferation	J:214772
	orthokeratosis	J:214772
	scaly skin	J:214772
	skin inflammation	J:214772
	thick epidermis stratum granulosum	J:214772
Krt2^{tm1b(KOMP)Wtsi}/Krt2⁺ C57BL/6N-Krt2^{tm1b(KOMP)Wtsi}/Ucd	abnormal kidney morphology	J:211773
	abnormal testis morphology	J:211773
	decreased grip strength	J:211773
	small testis	J:211773
Krt2^{tm1b(KOMP)Wtsi}/Krt2^{tm1b(KOMP)Wtsi} C57BL/6N-Krt2^{tm1b(KOMP)Wtsi}/Ucd	abnormal kidney morphology	J:211773
	enlarged kidney	J:211773
	polycystic kidney	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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