Ldha Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ldha
lactate dehydrogenase A
MGI:96759

30 phenotypes from 13 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ldha^a-m1Neu/Ldha^a-m1Neu C3.Cg-Ldha^a-m1Neu	decreased erythrocyte cell number	J:14326
	decreased hematocrit	J:14326
	decreased hemoglobin content	J:14326
	hemolytic anemia	J:14326
	increased circulating bilirubin level	J:14326
	increased heart weight	J:14326
	increased liver weight	J:14326
	increased lung weight	J:14326
	reticulocytosis	J:14326
Ldha^a-m1Neu/Ldha^a-m1Neu involves: 101/El * C3H/El	abnormal common myeloid progenitor cell morphology	J:132674
	abnormal erythrocyte morphology	J:132674
	abnormal leukocyte morphology	J:132674
	decreased erythrocyte cell number	J:132674
	decreased hematocrit	J:132674
	decreased hemoglobin content	J:132674
	hemolytic anemia	J:132674
	increased mean corpuscular volume	J:132674
	increased neutrophil cell number	J:132674
	increased spleen weight	J:132674
	reticulocytosis	J:132674
	spleen hyperplasia	J:132674
Ldha^a-m2Neu/Ldha⁺ C3.Cg-Ldha^a-m2Neu	normal hematopoietic system phenotype	J:1072
Ldha^a-m2Neu/Ldha^a-m2Neu C3.Cg-Ldha^a-m2Neu	embryonic lethality during organogenesis, complete penetrance	J:1072
Ldha^a-m3Neu/Ldha⁺ C3.Cg-Ldha^a-m3Neu	normal hematopoietic system phenotype	J:1072
Ldha^a-m3Neu/Ldha^a-m3Neu C3.Cg-Ldha^a-m3Neu	decreased body size	J:1072
	decreased hemoglobin content	J:1072
	embryonic lethality during organogenesis, incomplete penetrance	J:1072
	postnatal lethality, complete penetrance	J:1072
Ldha^a-m4Neu/Ldha⁺ C3.Cg-Ldha^a-m4Neu	normal hematopoietic system phenotype	J:1072
Ldha^a-m4Neu/Ldha^a-m4Neu C3.Cg-Ldha^a-m4Neu	embryonic lethality during organogenesis, complete penetrance	J:1072
Ldha^a-m5Neu/Ldha^a-m5Neu C3.Cg-Ldha^a-m5Neu	no abnormal phenotype detected	J:506
Ldha^a-m6Neu/Ldha^a-m6Neu C3.Cg-Ldha^a-m6Neu	normal hematopoietic system phenotype	J:7771
Ldha^a-m6Neu/Ldha^a-m6Neu C3.Cg-Ldha^a-m6Neu	no abnormal phenotype detected	J:506
Ldha^a-m7Neu/Ldha⁺ involves: 102/El * C3H/El	abnormal enzyme/coenzyme activity	J:65152
Ldha^a-m7Neu/Ldha^a-m7Neu involves: 102/El * C3H/El	abnormal enzyme/coenzyme activity	J:65152
Ldha^a-m7Neu/Ldha^a-m7Neu involves: 102/El * C3H/El	preweaning lethality, incomplete penetrance	J:65152
Ldha^a-m9Neu/Ldha⁺ involves: 102/El * C3H/El	abnormal enzyme/coenzyme activity	J:65152
Ldha^a-m9Neu/Ldha^a-m9Neu involves: 102/El * C3H/El	abnormal enzyme/coenzyme activity	J:65152
Ldha^a-m11Neu/Ldha^a-m11Neu C3H/El-Ldha^a-m11Neu	postnatal lethality, complete penetrance	J:45877
Ldha^a-m12Neu/Ldha^a-m12Neu C3H/El-Ldha^a-m12Neu	postnatal lethality, complete penetrance	J:45877
Ldha^b/Ldha^b involves: C57BL/6J * DBA/2J	no abnormal phenotype detected	J:13763
Ldha^l7R2-1R/Ldha^l7R2-1R involves: BJR	preweaning lethality, complete penetrance	J:73982
Ldha^{tm1a(EUCOMM)Wtsi}/Ldha⁺ B6JTyr;B6N-Ldha^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased circulating alanine transaminase level	J:175295
	decreased circulating alkaline phosphatase level	J:175295
	decreased circulating HDL cholesterol level	J:175295
	decreased lactate dehydrogenase level	J:175295
	decreased total body fat amount	J:165965

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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