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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lef1
lymphoid enhancer binding factor 1
MGI:96770
14 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+
Lef1tm1Hhx/Lef1tm1Hhx
Tg(GZMB-cre)1Jcb/0
involves: 129S4/SvJaeSor * C57BL/6 * FVB/N 		abnormal memory T cell physiology J:189838
decreased CD8-positive, alpha-beta T cell number J:189838
Lef1tm1Hhx/Lef1tm1Hhx
Tcf7tm1Cle/Tcf7tm1Cle
Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+
Tg(GZMB-cre)1Jcb/0
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N 		abnormal memory T cell physiology J:189838
decreased CD8-positive, alpha-beta T cell number J:189838
decreased tumor necrosis factor secretion J:189838
Lef1tm1Rug/Lef1tm1Rug
Tcf7tm1Cle/Tcf7tm1Cle
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal allantois morphology J:54101
abnormal ectomesenchyme morphology J:54101
abnormal embryonic tissue morphology J:54101
abnormal extraembryonic tissue morphology J:54101
abnormal limb bud morphology J:54101
abnormal neural tube morphology J:54101
absent apical ectodermal ridge J:54101
embryonic lethality during organogenesis, incomplete penetrance J:54101
incomplete somite formation J:54101
small embryonic telencephalon J:54101
small forelimb buds J:54101
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory