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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lhcgr
luteinizing hormone/choriogonadotropin receptor
MGI:96783
103 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lhcgrtm1(KOMP)Vlcg/Lhcgrtm1(KOMP)Vlcg
C57BL/6N-Lhcgrtm1(KOMP)Vlcg/Nju 		decreased brain size J:211773
decreased mean corpuscular volume J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
small heart J:211773
small liver J:211773
small lung J:211773
small spleen J:211773
small stomach J:211773
small thymus J:211773
thrombocytopenia J:211773
Lhcgrtm1.1Pnara/Lhcgr+
involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J 		abnormal adult Leydig cell differentiation J:203295
abnormal testosterone level J:203295
decreased circulating follicle stimulating hormone level J:203295
decreased circulating luteinizing hormone level J:203295
decreased testis weight J:203295
early sexual maturation J:203295
enlarged prostate gland J:203295
enlarged seminal vesicle J:203295
increased circulating testosterone level J:203295
increased epididymis weight J:203295
increased Leydig cell number J:203295
increased prostate gland weight J:203295
increased seminal vesicle weight J:203295
increased urine major urinary protein level J:203295
normal reproductive system phenotype J:203295
Lhcgrtm1Hht/Lhcgrtm1Hht
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal anogenital distance J:66818, J:105533
abnormal caput epididymis morphology J:105533
abnormal ejaculation J:105533
abnormal female reproductive system morphology J:66818
abnormal male reproductive system morphology J:66818
abnormal prostate gland morphology J:105533
abnormal reproductive system physiology J:66818
abnormal sexual interaction J:105533
abnormal sperm physiology J:105533
abnormal uterus morphology J:66818
absent corpus luteum J:66818
absent endometrial glands J:66818
absent estrous cycle J:66818
absent estrus J:66818
absent Leydig cells J:66818
absent mature ovarian follicles J:66818
arrest of spermatogenesis J:66818, J:105533
bulbourethral gland hypoplasia J:105533
cryptorchism J:66818, J:105533
decreased body weight J:66818
decreased circulating testosterone level J:66818, J:105533
decreased Leydig cell number J:66818, J:105533
decreased ovary secretion J:66818
decreased testes secretion J:66818
decreased testis weight J:66818, J:105533
delayed vaginal opening J:66818
enlarged adrenal glands J:105533
enlarged spleen J:105533
epididymis hypoplasia J:66818
epididymis inflammation J:105533
external male genitalia atrophy J:105533
female infertility J:66818
impaired ovarian folliculogenesis J:66818
increased adrenal gland weight J:105533
increased circulating follicle stimulating hormone level J:66818, J:105533
increased circulating luteinizing hormone level J:66818, J:105533
increased kidney weight J:105533
male infertility J:66818
oligozoospermia J:105533
prostate gland hypoplasia J:66818
prostate gland inflammation J:105533
reduced male fertility J:105533
reproductive system inflammation J:105533
scrotum hypoplasia J:66818, J:105533
seminal vesicle hypoplasia J:66818
small ovary J:66818
small penis J:66818, J:105533
small prostate gland anterior lobe J:105533
small seminal vesicle J:105533
small seminiferous tubules J:66818, J:105533
small testis J:66818
thin uterine horn J:66818
thin uterus J:66818
vas deferens hypoplasia J:105533
Lhcgrtm1Zmlei/Lhcgr+
either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6) 		decreased circulating testosterone level J:66817
increased circulating follicle stimulating hormone level J:66817
Lhcgrtm1Zmlei/Lhcgrtm1Zmlei
either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6) 		abnormal abdominal fat pad morphology J:66817
abnormal adult Leydig cell differentiation J:66817
abnormal anogenital distance J:66817
abnormal caput epididymis morphology J:82008
abnormal cauda epididymis morphology J:82008
abnormal epididymis epithelium morphology J:82008
abnormal epididymis morphology J:82008
abnormal female reproductive system morphology J:66817
abnormal ovary morphology J:66817
abnormal seminiferous tubule morphology J:66817
abnormal uterus morphology J:66817
abnormal vagina development J:66817
abnormal vagina orifice morphology J:66817
absent corpus luteum J:66817
absent estrous cycle J:66817
absent mature ovarian follicles J:66817
ambiguous external female genitalia J:66817
arrest of spermatogenesis J:66817
cryptorchism J:66817
decreased circulating estradiol level J:66817
decreased circulating progesterone level J:66817
decreased circulating testosterone level J:66817
decreased endometrial gland number J:66817
decreased epididymal cell proliferation J:82008
decreased epididymis weight J:66817
decreased Leydig cell number J:66817
decreased ovary weight J:66817
decreased seminal vesicle weight J:66817
decreased testis weight J:66817
epididymis hypoplasia J:66817
female infertility J:66817
impaired ovarian folliculogenesis J:66817
increased body weight J:66817
increased circulating estradiol level J:66817
increased circulating follicle stimulating hormone level J:66817
increased circulating luteinizing hormone level J:66817
increased male germ cell apoptosis J:82008
male infertility J:66817
prostate gland hypoplasia J:66817
seminal vesicle hypoplasia J:66817
small epididymis J:66817
small ovary J:66817
small penis J:66817
small prostate gland J:66817
small seminal vesicle J:66817
small seminiferous tubules J:66817
testis hypoplasia J:66817
thin endometrium J:66817
thin myometrium J:66817
thin uterus J:66817
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory