About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lhx2
LIM homeobox protein 2
MGI:96785
34 phenotypes from 8 alleles in 14 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Emx1tm1(cre)Krj/Emx1+
Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo
involves: 129S2/SvPas * C57BL/6 * SJL 		abnormal neocortex morphology J:154611
abnormal olfactory bulb morphology J:154611
abnormal olfactory cortex morphology J:154611
abnormal telencephalon morphology J:154611
telencephalon hypoplasia J:154611
Emx1tm1(cre)Krj/Emx1+
Lhx2tm1.1Ddmo/Lhx2tm1.2Ddmo
involves: 129S2/SvPas * C57BL/6 * SJL 		abnormal neocortex morphology J:154611
abnormal olfactory bulb morphology J:154611
abnormal olfactory cortex morphology J:154611
abnormal telencephalon morphology J:154611
telencephalon hypoplasia J:154611
Emx1tm1(cre)Yql/Emx1+
Lhx2tm1Monu/Lhx2tm1Monu
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal cerebral cortex morphology J:130167
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
Lhx2tm1Monu/Lhx2tm1Monu
involves: 129 * 129P2/OlaHsd * C57BL/6 		abnormal cerebral cortex morphology J:130167
abnormal telencephalon development J:130167
Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		normal nervous system phenotype J:154611
Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL 		abnormal neocortex morphology J:154611
Lhx2tm1.1Lcar/Lhx2tm1.1Lcar
involves: 129P2/OlaHsd 		normal vision/eye phenotype J:176341
Lhx2tm1.1Lcar/Lhx2tm1.1Lcar
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S4/SvJae * C57BL/6 * CBA 		abnormal hair cycle anagen phase J:159209
abnormal hair growth J:159209
Lhx2tm1.1Lcar/Lhx2tm1.1Lcar
Tg(Lhx2-cre)1Lcar/0
involves: 129P2/OlaHsd 		abnormal optic vesicle formation J:176341
anophthalmia J:176341
Lhx2tm1.1Lcar/Lhx2tm1Dra
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S4/SvJae * C57BL/6 * CBA 		abnormal hair cycle anagen phase J:159209
abnormal hair growth J:159209
Lhx2tm1.1Monu/Lhx2tm1.1Monu
involves: 129P2/OlaHsd 		abnormal cerebral cortex morphology J:130167
Lhx2tm1Dra/Lhx2tm1.1Monu
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal cerebral cortex morphology J:130167
Lhx2tm1Dra/Lhx2tm1Dra
involves: 129S4/SvJae 		abnormal basal ganglion morphology J:64676
abnormal cerebral cortex morphology J:64676
abnormal cortical plate morphology J:64676
abnormal erythropoiesis J:64676
abnormal eye development J:64676
abnormal neocortex morphology J:64676
abnormal olfactory bulb morphology J:123232
abnormal optic vesicle formation J:64676
abnormal telencephalon morphology J:64676
absent hippocampus J:64676
absent optic placodes J:64676
absent retina J:64676
anemia J:64676
anophthalmia J:64676
aphakia J:64676
decreased erythroid progenitor cell number J:64676
decreased hematocrit J:64676
flat forehead J:64676
forebrain hypoplasia J:64676
hydrops fetalis J:64676
lethality throughout fetal growth and development, complete penetrance J:64676
liver hypoplasia J:64676
pallor J:64676
small liver J:64676
Lhx2tm1Dra/Lhx2tm1Dra
involves: 129S4/SvJae * C57BL/6 		abnormal cerebral cortex morphology J:130167
Lhx2tm1Lcar/Lhx2tm1Lcar
involves: 129/Sv * C57BL/6 		anemia J:159209
anophthalmia J:159209
decreased hair follicle number J:159209
underdeveloped hair follicles J:159209
Lhx2tm1Monu/Lhx2tm1Dra
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA 		abnormal hair cycle anagen phase J:159209
abnormal hair growth J:159209
Lhx2tm1Monu/Lhx2tm1Monu
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA 		abnormal hair cycle anagen phase J:159209
abnormal hair growth J:159209
Lhx2tm1Monu/Lhx2tm1Monu
Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129P2/OlaHsd * CD-1 * FVB/N 		abnormal cerebral cortex morphology J:130167
abnormal telencephalon development J:130167
Tg(CAG-Bgeo/Lhx2,-GFP)#Lcar/0
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * CBA 		abnormal hair cycle J:159209
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory