Lifr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lifr
LIF receptor alpha
MGI:96788

33 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lifr^{tm1b(EUCOMM)Hmgu}/Lifr⁺ C57BL/6N-Lifr^{tm1b(EUCOMM)Hmgu}/H	abnormal brain morphology	J:211773
	decreased exploration in new environment	J:211773
Lifr^{tm1b(EUCOMM)Hmgu}/Lifr^{tm1b(EUCOMM)Hmgu} C57BL/6N-Lifr^{tm1b(EUCOMM)Hmgu}/H	preweaning lethality, complete penetrance	J:211773
Lifr^tm1Cgre/Lifr^tm1Cgre either: (involves: 129P2/OlaHsd * CBA) or (involves: 129P2/OlaHsd * MF1)	decreased body weight	J:82048
	decreased motor neuron number	J:82048
	neonatal lethality, complete penetrance	J:82048
Lifr^tm1Imx/Lifr⁺ B6;129S7-Lifr^tm1Imx/J	abnormal ureter morphology	J:242320
	cryptorchism	J:242320
	hydroureter	J:242320
Lifr^tm1Imx/Lifr^tm1Imx B6;129S7-Lifr^tm1Imx/J	abnormal kidney development	J:242320
	abnormal kidney morphology	J:242320
	abnormal renal/urinary system morphology	J:242320
	abnormal ureter morphology	J:242320
	abnormal ureter smooth muscle morphology	J:242320
	blind ureter	J:242320
	cryptorchism	J:242320
	decreased fetal size	J:242320
	decreased nephron number	J:242320
	decreased renal glomerulus number	J:242320
	ectopic ureter	J:242320
	hydronephrosis	J:242320
	hydroureter	J:242320
	prenatal lethality, incomplete penetrance	J:242320
	renal hypoplasia	J:242320
	small kidney	J:242320
Lifr^tm1Imx/Lifr^tm1Imx involves: 129P3/J * 129S7/SvEvBrd * C57BL/6	abnormal astrocyte morphology	J:25253
	abnormal dorsal root ganglion morphology	J:25253
	abnormal long bone morphology	J:25253
	abnormal metacarpal bone morphology	J:25253
	abnormal placenta morphology	J:25253
	decreased body size	J:25253
	decreased bone mineral density	J:25253
	decreased bone volume	J:25253
	embryonic lethality before implantation, incomplete penetrance	J:25253
	increased liver glycogen level	J:25253
	increased osteoclast cell number	J:25253
	neonatal lethality, complete penetrance	J:25253

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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