Loricrin Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Loricrin
loricrin cornified envelope precursor protein
MGI:96816

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Loricrin^{tm1.1(KOMP)Vlcg}/Loricrin⁺ C57BL/6N-Loricrin^{tm1.1(KOMP)Vlcg}/Ucd	abnormal liver morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal uterus morphology	J:211773
	abnormal vibrissa morphology	J:211773
	enlarged spleen	J:211773
	enlarged uterus	J:211773
	improved glucose tolerance	J:211773
	increased kidney weight	J:211773
	small testis	J:211773
Loricrin^{tm1.1(KOMP)Vlcg}/Loricrin^{tm1.1(KOMP)Vlcg} C57BL/6N-Loricrin^{tm1.1(KOMP)Vlcg}/Ucd	abnormal skin morphology	J:211773
	abnormal testis morphology	J:211773
	increased kidney weight	J:211773
	increased spleen weight	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	small testis	J:211773
Loricrin^tm1Der/Loricrin^tm1Der FVB.129S7-Loricrin^tm1Der	abnormal epidermis stratum corneum morphology	J:65187
	abnormal skin condition	J:65187
	decreased body size	J:65187
	decreased skin tensile strength	J:65187
	erythroderma	J:65187
	impaired skin barrier function	J:65187
	translucent skin	J:65187

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24