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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Anxa1
annexin A1
MGI:96819
52 phenotypes from 2 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Anxa1em1(IMPC)Ccpcz/Anxa1em1(IMPC)Ccpcz
C57BL/6NCrl-Anxa1em1(IMPC)Ccpcz/Ccpcz 		abnormal epididymis morphology J:211773
abnormal heart morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
abnormal uterus morphology J:211773
decreased circulating iron level J:211773
enlarged epididymis J:211773
enlarged heart J:211773
enlarged spleen J:211773
enlarged thymus J:211773
enlarged uterus J:211773
increased airway resistance J:211773
increased circulating alanine transaminase level J:211773
small kidney J:211773
small spleen J:211773
Anxa1tm1Rjf/Anxa1+
Not Specified 		increased inflammatory response J:81498
Anxa1tm1Rjf/Anxa1tm1Rjf
involves: 129 * C57BL 		abnormal adrenal gland secretion J:129587
abnormal corticotroph morphology J:135972
abnormal folliculo-stellate cell morphology J:135972
abnormal gonadotroph morphology J:135972
abnormal lactotroph morphology J:135972
abnormal somatotroph morphology J:135972
decreased corticotroph cell size J:135972
normal homeostasis/metabolism phenotype J:129587, J:135972
increased adrenocorticotropin level J:135972
thin adrenal cortex J:129587
Anxa1tm1Rjf/Anxa1tm1Rjf
involves: 129 * C57BL/6 		abnormal tumor vascularization J:153690
abnormal vascular endothelial cell migration J:153690
abnormal vascular endothelial cell physiology J:153690
decreased metastatic potential J:153690
decreased susceptibility to induced morbidity/mortality J:153690
decreased tumor growth/size J:153690
decreased vascular endothelial cell proliferation J:153690
delayed wound healing J:153690
Anxa1tm1Rjf/Anxa1tm1Rjf
involves: BALB/c 		abnormal colon morphology J:142735
abnormal intestinal epithelium morphology J:142735
increased susceptibility to induced colitis J:142735
increased susceptibility to xenobiotic induced morbidity/mortality J:142735
weight loss J:142735
Anxa1tm1Rjf/Anxa1tm1Rjf
involves: C57BL/6 		abnormal cranium morphology J:129618
abnormal frontal bone morphology J:129618
abnormal neurocranium morphology J:129618
abnormal palatine bone morphology J:129618
abnormal sagittal suture morphology J:129618
ectopic cranial bone J:129618
increased bone mineral density J:129618
Anxa1tm1Rjf/Anxa1tm1Rjf
Not Specified 		abnormal adipose tissue morphology J:115806
abnormal adipose tissue physiology J:115806
abnormal fat pad morphology J:115806
abnormal leukocyte physiology J:81498
delayed wound healing J:194294
impaired macrophage phagocytosis J:81498
increased circulating insulin level J:115806
increased inflammatory response J:81498
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory