Lpl Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lpl
lipoprotein lipase
MGI:96820

38 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lpl^tm1Bres/Lpl⁺ involves: 129S4/SvJae	increased body weight	J:134171
	increased cholesterol level	J:134171
	increased total fat pad weight	J:134171
	increased triglyceride level	J:134171
Lpl^tm1Bres/Lpl⁺ involves: 129S4/SvJae * C57BL/6J	abnormal lipid homeostasis	J:30062
	increased circulating cholesterol level	J:30062
	increased circulating triglyceride level	J:30062
	increased circulating VLDL cholesterol level	J:30062
	increased circulating VLDL triglyceride level	J:30062
Lpl^tm1Bres/Lpl^tm1Bres involves: 129S4/SvJae * C57BL/6J	abnormal adipose tissue morphology	J:30062
	abnormal capillary morphology	J:30062
	abnormal lipid homeostasis	J:30062
	abnormal liver morphology	J:30062
	abnormal lung vasculature morphology	J:30062
	abnormal pulmonary alveolus morphology	J:30062
	abnormal skeletal muscle morphology	J:30062
	cyanosis	J:30062
	decreased circulating HDL cholesterol level	J:30062
	decreased circulating LDL cholesterol level	J:30062
	increased circulating cholesterol level	J:30062
	increased circulating triglyceride level	J:30062
	increased circulating VLDL cholesterol level	J:30062
	neonatal lethality, complete penetrance	J:30062
	pallor	J:30062
Lpl^tm1Ijg/Lpl^tm1Ijg Tg(Myh6-cre)2182Mds/? involves: C57BL/6	abnormal glucose homeostasis	J:90737
	abnormal lipid level	J:90737
	decreased cardiac muscle triglyceride level	J:90737
	decreased fatty acids level	J:90737
	increased cardiac muscle cell glucose uptake	J:90737
	increased circulating triglyceride level	J:90737
	increased circulating VLDL triglyceride level	J:90737
Lpl^tm1Ijg/Lpl^tm1Ijg Tg(Myh6-cre)2182Mds/0 involves: FVB/N	abnormal cardiovascular system physiology	J:110484
	abnormal glucose homeostasis	J:110484
	cardiac fibrosis	J:110484
	cardiac interstitial fibrosis	J:110484
	decreased heart left ventricle muscle contractility	J:110484
	increased cardiac muscle cell glucose uptake	J:110484
	increased circulating triglyceride level	J:110484
	increased left ventricle diastolic pressure	J:110484
	increased left ventricle systolic pressure	J:110484
	increased susceptibility to induced morbidity/mortality	J:110484
Lpl^tm1Sem/Lpl⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal lipid homeostasis	J:25652
	increased circulating cholesterol level	J:25652
	increased circulating HDL cholesterol level	J:25652
	increased circulating phospholipid level	J:25652
	increased circulating triglyceride level	J:25652
	increased circulating VLDL triglyceride level	J:25652
Lpl^tm1Sem/Lpl^tm1Sem involves: 129P2/OlaHsd * C57BL/6J	atelectasis	J:25652
	decreased circulating HDL cholesterol level	J:25652
	hyperlipidemia	J:25652
	increased circulating cholesterol level	J:25652
	increased circulating phospholipid level	J:25652
	increased circulating triglyceride level	J:25652
	liver vascular congestion	J:25652
	neonatal lethality, complete penetrance	J:25652
	pulmonary vascular congestion	J:25652

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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