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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Maf
MAF bZIP transcription factor
MGI:96909
72 phenotypes from 10 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mafem1(IMPC)Mbp/Maf+
C57BL/6N-Mafem1(IMPC)Mbp/MbpMmucd 		abnormal heart morphology J:211773
abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal ovary morphology J:211773
abnormal placenta morphology J:211773
abnormal spleen morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
decreased prepulse inhibition J:211773
enlarged heart J:211773
enlarged kidney J:211773
enlarged ovary J:211773
enlarged spleen J:211773
increased circulating bilirubin level J:211773
increased freezing behavior J:211773
increased grip strength J:211773
microphthalmia J:211773
small kidney J:211773
small liver J:211773
small spleen J:211773
urinary bladder obstruction J:211773
Mafem1(IMPC)Mbp/Mafem1(IMPC)Mbp
C57BL/6N-Mafem1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal liver size J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
edema J:211773
embryonic growth retardation J:211773
microphthalmia J:211773
preweaning lethality, complete penetrance J:211773
MafENU424/Maf+
involves: 102/El * C3H/El * C57BL/6El 		nuclear cataract J:121758
MafENU424/MafENU424
involves: 102/El * C3H/El * C57BL/6El 		nuclear cataract J:121758
MafOfl/Maf+
either: 102/ElH or C3H/HeH 		abnormal pupillary reflex J:82475
cataract J:82475
MafOfl/MafOfl
either: 102/ElH or C3H/HeH 		abnormal kidney morphology J:82475
abnormal lens induction J:82475
decreased body size J:82475
dilated renal tubule J:82475
increased urine glucose level J:82475
microphthalmia J:82475
neonatal lethality, incomplete penetrance J:82475
postnatal lethality, complete penetrance J:82475
small pupil J:82475
tremors J:82475
tubular nephritis J:82475
Maftm1.1Cbm/Maftm2.1Cbm
Isl1tm1(cre)Tmj/Isl1+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL 		abnormal axon morphology J:181639
abnormal coat/ hair morphology J:181639
abnormal Meissner's corpuscle morphology J:181639
abnormal nervous system electrophysiology J:181639
abnormal pacinian corpuscle morphology J:181639
axon degeneration J:181639
decreased body weight J:181639
decreased nerve conduction velocity J:181639
decreased pacinian corpuscle number J:181639
impaired coordination J:181639
small pacinian corpuscles J:181639
Maftm1Glm/Maftm1Glm
involves: 129/Sv * BALB/c 		abnormal lens development J:54079
abnormal lens morphology J:54079
decreased body size J:54079
decreased interleukin-4 secretion J:78382
lethality throughout fetal growth and development, incomplete penetrance J:54079
microphthalmia J:54079
perinatal lethality, incomplete penetrance J:54079
postnatal lethality, incomplete penetrance J:54079
normal vision/eye phenotype J:54079
Maftm1Gsb/Maftm1Gsb
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal cornea endothelium morphology J:56583
abnormal eating behavior J:56583
abnormal lens development J:56583
abnormal lens vesicle development J:56583
increased cornea thickness J:56583
neonatal lethality, complete penetrance J:56583
shortened head J:56583
small lens J:56583
weakness J:56583
Maftm1Mym/Maftm1Mym
either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * ICR) 		abnormal lens development J:56095
abnormal lens fiber morphology J:56095
embryonic lethality during organogenesis, incomplete penetrance J:56095
postnatal lethality, complete penetrance J:56095
Tg(Igh-Maf)68Staka/0
C57BL/6-Tg(Igh-Maf)68Staka 		abnormal spleen morphology J:168074
enlarged spleen J:168074
increased IgG level J:168074
increased IgM level J:168074
increased immunoglobulin level J:168074
increased lymphoma incidence J:168074
increased plasma cell number J:168074
renal cast J:168074
Tg(Igh-Maf)524Staka/0
involves: C57BL/6 * C57BL/6J * DBA/2 		abnormal spleen morphology J:168074
enlarged spleen J:168074
increased IgG level J:168074
increased IgM level J:168074
increased immunoglobulin level J:168074
increased lymphoma incidence J:168074
increased plasma cell number J:168074
renal cast J:168074
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory