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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ascl2
achaete-scute family bHLH transcription factor 2
MGI:96920
16 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ascl2tm1.1Cle/Ascl2tm1.1Cle
Tg(Cyp1a1-cre)1Dwi/0
involves: 129P2/OlaHsd * C57BL/6 * CBA 		abnormal small intestine crypts of Lieberkuhn morphology J:148715
increased small intestinal crypt cell apoptosis J:148715
Ascl2tm1.1Nagy/Ascl2+
involves: 129S1/Sv * 129X1/SvJ * CD-1 		decreased spongiotrophoblast cell number J:57828
Ascl2tm1Alj/Ascl2+
involves: 129 * CD-1 		abnormal chorion morphology J:23260
abnormal spongiotrophoblast layer morphology J:23260
paternal imprinting J:23260
postnatal lethality, complete penetrance J:23260
Ascl2tm1Alj/Ascl2tm1Alj
either: (involves: 129) or (involves: 129 * CD-1) 		abnormal chorion morphology J:20553
abnormal placenta development J:20553
abnormal placental labyrinth vasculature morphology J:20553
absent spongiotrophoblast J:20553
embryonic lethality during organogenesis, complete penetrance J:20553
Ascl2tm1Alj/Ascl2tm1Alj
involves: 129 * CD-1 		abnormal chorion morphology J:23260
absent spongiotrophoblast J:23260
embryonic lethality during organogenesis, complete penetrance J:23260
Ascl2tm2Nagy/Ascl2tm2Nagy
involves: 129S1/Sv * 129X1/SvJ * Hsd:ICR 		no abnormal phenotype detected J:153719
Tg(Vil1-Ascl2)1Cle/?
involves: C57BL/6 * CBA 		abnormal ileum crypts of Lieberkuhn morphology J:148715
abnormal small intestinal villus morphology J:148715
branched small intestinal villi J:148715
decreased small intestinal villus height J:148715
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory