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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mbl2
mannose-binding lectin (protein C) 2
MGI:96924
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fcnatm1Tefu/Fcnatm1Tefu
Mbl1tm1Kata/Mbl1tm1Kata
Mbl2tm1Kata/Mbl2tm1Kata
involves: 129S4/SvJae 		normal immune system phenotype J:177350
Mbl1tm1Kata/Mbl1tm1Kata
Mbl2tm1Kata/Mbl2tm1Kata
involves: 129 * C57BL/6 		abnormal B cell number J:97686
abnormal circulating interleukin-6 level J:98124
abnormal circulating tumor necrosis factor level J:98124
decreased germinal center B cell number J:97686
decreased macrophage cell number J:98124
decreased monocyte cell number J:98124
impaired macrophage phagocytosis J:97686, J:98124
increased B-1 B cell number J:97686
increased susceptibility to bacterial infection J:98124
Mbl1tm1Kata/Mbl1tm1Kata
Mbl2tm1Kata/Mbl2tm1Kata
involves: 129 * C57BL/6J 		abnormal complement pathway J:106351
abnormal response to infection J:106352
decreased susceptibility to kidney reperfusion injury J:106351
increased susceptibility to bacterial infection J:106353
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory