Mbp Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mbp
myelin basic protein
MGI:96925

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Mbp^shi-mld/Mbp^shi-mld involves: MDB/Dt	abnormal behavior	J:5917
	premature death	J:5917
	sporadic seizures	J:5917
	tremors	J:5917
Mbp^shi/Mbp⁺ Mobp^tm1Irg/Mobp⁺ involves: 129S1/SvImJ * C57BL/6J * SWV	normal nervous system phenotype	J:104861
Mbp^shi/Mbp^shi Plp1^tm1Kan/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SWV	abnormal myelin sheath morphology	J:38856
	abnormal myelination	J:38856
	ataxia	J:38856
	normal mortality/aging	J:38856
	tremors	J:38856
Mbp^shi/Mbp^shi Plp1^tm1Kan/Y involves: 129S1/Sv * 129X1/SvJ * SWV	axonal spheroids	J:48031
	demyelination	J:48031
Mbp^shi/Mbp^shi Pmp2^{tm1.1(KOMP)Vlcg}/Pmp2^{tm1.1(KOMP)Vlcg} involves: C3HeB/FeJ * C57BL/6 * C57BL/6NTac	abnormal myelin sheath morphology	J:211344
	decreased nerve conduction velocity	J:211344
	limb grasping	J:211344
	tremors	J:211344

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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