About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
MGI:96955
24 phenotypes from 4 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Cd19tm1(cre)Cgn/Cd19+
Slc3a2tm1.1Mgin/Slc3a2tm1.1Mgin
involves: 129 * C57BL/6 * SJL 		abnormal B cell activation J:148000
abnormal B cell physiology J:148000
abnormal class switch recombination J:148000
abnormal plasma cell differentiation J:148000
decreased B cell proliferation J:148000
decreased germinal center B cell number J:148000
decreased IgG level J:148000
decreased IgM level J:148000
normal immune system phenotype J:148000
Cd19tm1(cre)Cgn/Cd19+
Slc3a2tm1.1Mgin/Slc3a2tm1Yai
involves: 129 * C57BL/6 * SJL 		decreased IgG3 level J:148000
decreased IgM level J:148000
Slc3a2tm1.1Merl/Slc3a2+
Tg(Vil1-cre)997Gum/0
B6.Cg-Slc3a2tm1.1Merl Tg(Vil1-cre)997Gum 		abnormal enterocyte proliferation J:173946
decreased incidence of tumors by chemical induction J:173946
decreased susceptibility to induced colitis J:173946
decreased susceptibility to weight loss J:173946
decreased susceptibility to xenobiotic induced morbidity/mortality J:173946
decreased tumor growth/size J:173946
Slc3a2tm1.1Merl/Slc3a2tm1.1Merl
Tg(Vil1-cre)997Gum/0
B6.Cg-Slc3a2tm1.1Merl Tg(Vil1-cre)997Gum 		preweaning lethality, incomplete penetrance J:173946
Slc3a2tm1.1Mgin/Slc3a2tm1.1Mgin
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal cell morphology J:134813
Slc3a2tm1.1Yait/Slc3a2tm1.1Yait
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6NCrSlc 		abnormal macrophage antigen presentation J:188365
abnormal macrophage differentiation J:188365
abnormal macrophage morphology J:188365
abnormal macrophage physiology J:188365
impaired macrophage phagocytosis J:188365
Slc3a2tm1Yai/Slc3a2tm1Yai
involves: 129X1/SvJ * C57BL/6 		embryonic lethality, complete penetrance J:93968
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory