Rab8a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rab8a
RAB8A, member RAS oncogene family
MGI:96960

9 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rab8a^em1(IMPC)J/Rab8a⁺ C57BL/6NJ-Rab8a^em1(IMPC)J/Mmjax	decreased lean body mass	J:211773
Rab8a^em1(IMPC)J/Rab8a⁺ C57BL/6NJ-Rab8a^em1(IMPC)J/Mmjax	increased grip strength	J:211773
Rab8a^tm1.1Aha/Rab8a^tm1.1Aha Tg(Vil1-cre)997Gum/? involves: C57BL/6 * SJL	premature death	J:123415
Rab8a^tm1.1Aha/Rab8a^tm1.2Aha Tg(Vil1-cre)997Gum/? involves: C57BL/6 * SJL	premature death	J:123415
Rab8a^tm1.2Aha/Rab8a^tm1.2Aha involves: C57BL/6 * SJL	abnormal intestinal absorption	J:123415
	abnormal small intestine morphology	J:123415
	accumulation of giant lysosomes in kidney/renal tubule cells	J:123415
	cachexia	J:123415
	decreased small intestinal microvillus size	J:123415
	diarrhea	J:123415
	premature death	J:123415
Rab8a^tm1.2Aha/Rab8a^tm1.2Aha Not Specified	premature death	J:211898
Rab8a^tm1Aha/Rab8a^tm1Aha Not Specified	abnormal intestinal absorption	J:123415
	abnormal small intestine morphology	J:123415
	accumulation of giant lysosomes in kidney/renal tubule cells	J:123415
	cachexia	J:123415
	decreased small intestinal microvillus size	J:123415
	diarrhea	J:123415
	premature death	J:123415

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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