Mgat1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mgat1
mannoside acetylglucosaminyltransferase 1
MGI:96973

33 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mgat1^{tm1b(EUCOMM)Hmgu}/Mgat1⁺ C57BL/6N-Mgat1^{tm1b(EUCOMM)Hmgu}/Ieg	decreased cardiac stroke volume	J:211773
	decreased exploration in new environment	J:211773
	decreased red blood cell distribution width	J:211773
Mgat1^{tm1b(EUCOMM)Hmgu}/Mgat1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Mgat1^{tm1b(EUCOMM)Hmgu}/Ieg	preweaning lethality, complete penetrance	J:211773
Mgat1^tm1Jxm/Mgat1^tm1Jxm involves: 129S2/SvPas * C57BL/6J	abnormal direction of heart looping	J:68330
	abnormal embryonic neuroepithelial layer differentiation	J:68330
	abnormal left-right axis patterning	J:68330
	abnormal neural tube morphology	J:68330
	abnormal tail position or orientation	J:68330
	abnormal vascular development	J:68330
	abnormal vascular endothelial cell morphology	J:68330
	anemia	J:68330
	decreased embryo size	J:68330
	embryonic growth arrest	J:68330
	embryonic lethality during organogenesis, complete penetrance	J:68330
	hemorrhage	J:68330
	incomplete embryo turning	J:68330
	incomplete somite formation	J:68330
	situs inversus	J:68330
Mgat1^tm1Pst/Mgat1^tm1Pst involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 * SJL	decreased embryo size	J:16489
	embryonic growth retardation	J:16489
	embryonic lethality during organogenesis, complete penetrance	J:16489
	hemorrhage	J:16489
	incomplete caudal neuropore closure	J:16489
	incomplete rostral neuropore closure	J:16489
	incomplete somite formation	J:16489
	pallor	J:16489
Mgat1^tm2Jxm/Mgat1^tm1Pst Tg(Zp3-cre)1Gwh/0 involves: 129/Sv * C57BL/6 * SJL	abnormal oogenesis	J:94224
	abnormal zona pellucida morphology	J:94224
	decreased litter size	J:94224
	reduced female fertility	J:94224
	thin zona pellucida	J:94224
Mgat1^tm2Jxm/Mgat1^tm2Jxm Tg(Stra8-icre)1Reb/0 involves: 129S1/Sv * 129X1/SvJ * FVB/NJ	abnormal spermatid morphology	J:260130
	arrest of spermatogenesis	J:260130
	azoospermia	J:260130
	male infertility	J:260130
	multinucleated giant male germ cells	J:260130
Mgat1^tm2Jxm/Mgat1^tm2Jxm Tg(Zp3-cre)1Gwh/0 Not Specified	abnormal oogenesis	J:94224
	abnormal zona pellucida morphology	J:94224
	decreased litter size	J:94224
	reduced female fertility	J:94224
	thin zona pellucida	J:94224

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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