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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kitl
kit ligand
MGI:96974
90 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Adam10Pied/Adam10+
Hrhr/Hrhr
Tg(KRT14-Kitl*)4XTG2Bjl/0
involves: C57BL/6J * HRA/SkhKcl * SJL 		abnormal skin pigmentation J:262499
hairless J:262499
Baxtm1Sjk/Bax+
KitlSl/KitlSl
Tg(Pou5f1-GFP)1Scho/?
involves: 129X1/SvJ * C3H * CD-1 * FVB 		abnormal primordial germ cell proliferation J:115283
Baxtm1Sjk/Baxtm1Sjk
KitlSl/KitlSl
Tg(Pou5f1-GFP)1Scho/?
involves: 129X1/SvJ * C3H * CD-1 * FVB 		abnormal primordial germ cell migration J:115283
abnormal primordial germ cell proliferation J:115283
KitlSl-10H/Kitl+
involves: 101/H * C3H/HeH 		abnormal foot pigmentation J:14014
diluted coat color J:14014
head spot J:14014
white spotting J:14014
KitlSl-10H/KitlSl-10H
involves: 101/H * C3H/HeH 		anemia J:14014, J:31566
lethality throughout fetal growth and development, complete penetrance J:31566
KitlSl-18H/Kitl+
involves: 101/H * C3H/HeH 		anemia J:18280
belly spot J:18280
diluted coat color J:18280
head blaze J:18280
head spot J:18280
hypopigmentation J:18280
pallor J:18280
postnatal lethality, incomplete penetrance J:18280
white spotting J:18280
KitlSl-18H/Kitl+
X/SryAKR/J
involves: AKR/J * C57BL/6J 		decreased testis weight J:133266
KitlSl-18H/KitlSl-18H
involves: 101/H * C3H/HeH 		embryonic lethality J:18280
embryonic lethality between implantation and somite formation J:18280
KitlSl-18H/KitlSl-con
Not Specified 		diluted coat color J:18280
head blaze J:18280
KitlSl-d/Kitl+
rs/rs
involves: C3H/HeJ * DBA/2J 		absent coat pigmentation J:125080
KitlSl-d/Kitl+
Ph/Ph+
involves: C57BL/Gr * DBA/2J 		abnormal coat/hair pigmentation J:125080
head spot J:125080
irregular coat pigmentation J:125080
KitlSl-d/KitlSl-d
Tg(Mt1-RET)304Ina/0
involves: BALB/c * C57BL/6 * DBA/2 		decreased tumor incidence J:88074
increased melanoma incidence J:88074
KitlSl-gb/Kitl+
C3.Cg-KitlSl-gb 		abnormal ventral coat pigmentation J:79293
head spot J:79293
increased mean corpuscular hemoglobin J:79293
increased mean corpuscular volume J:79293
macrocytic anemia J:79293
KitlSl-gb/KitlSl-gb
C3.Cg-KitlSl-gb 		abnormal primordial germ cell migration J:115437
abnormal primordial germ cell morphology J:115437
abnormal primordial germ cell proliferation J:115437
absent primordial germ cells J:115437
decreased primordial germ cell number J:115437
increased primordial germ cell apoptosis J:115437
lethality throughout fetal growth and development, incomplete penetrance J:79293
low mean erythrocyte cell number J:79293
macrocytic anemia J:79293
perinatal lethality, complete penetrance J:79293
prenatal lethality, incomplete penetrance J:79293
KitlSl-J/Kitl+
C3HeB/FeHu-KitlSl-J 		belly spot J:145144
diluted coat color J:145144
white spotting J:145144
KitlSl-J/Kitl+
involves: 129 		increased testicular teratoma incidence J:50508
KitlSl-J/KitlSl-J
C3HeB/FeHu-KitlSl-J 		abnormal seminiferous tubule morphology J:145144
absent germ cells J:145144
absent ovarian follicles J:145144
anemia J:145144
perinatal lethality, complete penetrance J:145144
KitlSl-pan/Kitl+
either: (involves: C3H/HeJ * C57BL/6J) or (involves: C3H/HeN * C57BL/6J) 		decreased primordial germ cell number J:23593
diluted coat color J:23593
normal reproductive system phenotype J:23593
KitlSl-pan/KitlSl-pan
either: (involves: C3H/HeJ * C57BL/6J) or (involves: C3H/HeN * C57BL/6J) 		decreased oocyte number J:23593
decreased primordial germ cell number J:23593
female infertility J:23593
impaired ovarian folliculogenesis J:23593
normal reproductive system phenotype J:23593
white spotting J:23593
KitlSl-pan/KitlSl-pan
involves: C3H 		decreased male germ cell number J:4746
decreased oocyte number J:4746
decreased primordial germ cell number J:4746
female infertility J:4746
impaired ovarian folliculogenesis J:4746
irregular coat pigmentation J:4746
macrocytic anemia J:4746
small ovary J:4746
white spotting J:4746
KitlSl/Kitl+
either: (involves: C3H * WC) or (involves: C3H * C57BL/6 * DBA/2J * WC) 		anemia J:6084
decreased mast cell number J:6084
KitlSl/Kitl+
involves: 129/Sv * C3H 		increased testicular teratoma incidence J:50508
increased tumor incidence J:50508
KitlSl/Kitl+
involves: C3H 		abnormal vibrissa morphology J:3399
anemia J:3399
belly spot J:3399, J:157170
decreased ear pigmentation J:3399
decreased erythrocyte cell number J:3399
decreased foot pigmentation J:3399
diluted coat color J:3399, J:157170
head blaze J:3399
head spot J:3399
pallor J:3399
normal reproductive system phenotype J:3399
KitlSl/Kitl+
Tg(PGK1-KITLG*220)441Daw/0
involves: C3H 		abnormal coat/hair pigmentation J:32600
decreased mast cell number J:32600
hypopigmentation J:32600
KitlSl/KitlSl-17J
involves: BALB/cGr * C3HeB/FeJ 		absent coat pigmentation J:79402
KitlSl/KitlSl-Clo
Not Specified 		abnormal coat/hair pigmentation J:13654
absent coat pigmentation J:13654
KitlSl/KitlSl-d
(WC/ReJ KitlSl x B6.D2-KitlSl-d/J)F1-KitlSl/KitlSl-d/J 		abnormal osteoblast physiology J:111273
abnormal osteoclast morphology J:111273
abnormal skeleton development J:111273
decreased body weight J:111273
decreased bone mineral content J:111273
decreased bone mineral density J:111273
decreased compact bone thickness J:111273
decreased trabecular bone volume J:111273
increased erythrocyte protoporphyrin level J:5985
postnatal growth retardation J:111273
KitlSl/KitlSl-d
involves: C3H * C57BL/6 * DBA/2J * WC 		abnormal response to transplant J:6084
decreased mast cell number J:6084
KitlSl/KitlSl-d
involves: C57BL/6 * WC 		abnormal forestomach morphology J:2777
abnormal stomach epithelium morphology J:2777
abnormal stomach non-glandular epithelium morphology J:2777
abnormal tumor incidence J:5758
anemia J:2777, J:27511
decreased hematocrit J:27511
decreased primordial germ cell number J:5547
dermatitis J:5758
gastric ulcer J:2777
increased leukemia incidence J:5758
increased papilloma incidence J:2777
infertility J:5547
premature death J:5758
normal reproductive system phenotype J:5547
reticulocytosis J:27511
stomach inflammation J:2777
thymus atrophy J:5758
weight loss J:5758
KitlSl/KitlSl
involves: C3H 		abnormal blood circulation J:3399
abnormal brain development J:3399
absent skin pigmentation J:28098
anemia J:3399
infertility J:5547
lethality throughout fetal growth and development, complete penetrance J:3399
myelencephalic blebs J:3399
pallor J:3399
spina bifida J:3399
Kitltm2.1Pbes/KitlSl
involves: 129S1/Sv * C3H * C57BL/6J * FVB/N 		azoospermia J:157170
diluted coat color J:157170
Mc1re/Mc1re
Tg(KRT14-Kitl)1Takk/0
involves: C57BL/6 * SJL 		abnormal melanogenesis J:112959
Mc1re/Mc1re
Xpctm1Brd/Xpctm1Brd
Tg(KRT14-Kitl)1Takk/0
involves: 129S7/SvEvBrd * C57BL/6 * SJL 		increased squamous cell carcinoma incidence J:112959
increased tumor incidence J:112959
skin lesions J:112959
thick epidermis J:112959
weight loss J:112959
Xpatm1Tnka/Xpatm1Tnka
Tg(KRT14-Kitl)1Takk/?
involves: C57BL/6 * CBA * SJL 		abnormal coat/hair pigmentation J:100608
abnormal epidermal pigmentation J:100608
increased metastatic potential J:100608
increased skin tumor incidence J:100608
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory