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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mmp2
matrix metallopeptidase 2
MGI:97009
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mmp2tm1Ito/Mmp2tm1Ito
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129P2/OlaHsd * 129S6/SvEvTac 		decreased susceptibility to induced choroidal neovascularization J:86805
Mmp2tm1Ito/Mmp2tm1Ito
Recktm1Ito/Recktm1Ito
involves: 129P2/OlaHsd * C57BL/6 		embryonic lethality during organogenesis, complete penetrance J:107674
Mmp2tm1Ito/Mmp2tm1Ito
Timp1tm1Pds/Timp1tm1Pds
either: (involves: 129S4/SvJae) or (involves: C57BL/6) 		decreased susceptibility to bacterial infection J:94836
Mmp2tm1Ito/Mmp2tm1Ito
Timp3tm1Osya/Timp3tm1Osya
involves: 129P2/OlaHsd * C57BL/6 		abnormal abdominal aorta morphology J:193744
abnormal aorta wall morphology J:193744
aortitis J:193744
increased susceptibility to induced aneurysm formation J:193744
increased susceptibility to induced morbidity/mortality J:193744
Mmp2tm1Ito/Mmp2tm1Ito
Timp4tm1Vuo/Timp4tm1Vuo
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		normal cardiovascular system phenotype J:165901
Mmp14tm1Noda/Mmp14+
Mmp2tm1Ito/Mmp2tm1Ito
Not Specified 		decreased body weight J:91198
Mmp14tm1Noda/Mmp14tm1Noda
Mmp2tm1Ito/Mmp2tm1Ito
Not Specified 		abnormal blood vessel morphology J:91198
abnormal bone ossification J:91198
abnormal skeletal muscle morphology J:91198
abnormal skeleton morphology J:91198
cyanosis J:91198
decreased birth weight J:91198
delayed muscle development J:91198
neonatal lethality, complete penetrance J:91198
thin diaphragm muscle J:91198
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/03/2024
MGI 6.24 		The Jackson Laboratory