Mmp2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mmp2
matrix metallopeptidase 2
MGI:97009

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Mmp2^tm1Ito/Mmp2^tm1Ito Mmp9^tm1Tvu/Mmp9^tm1Tvu involves: 129P2/OlaHsd * 129S6/SvEvTac	decreased susceptibility to induced choroidal neovascularization	J:86805
Mmp2^tm1Ito/Mmp2^tm1Ito Reck^tm1Ito/Reck^tm1Ito involves: 129P2/OlaHsd * C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:107674
Mmp2^tm1Ito/Mmp2^tm1Ito Timp1^tm1Pds/Timp1^tm1Pds either: (involves: 129S4/SvJae) or (involves: C57BL/6)	decreased susceptibility to bacterial infection	J:94836
Mmp2^tm1Ito/Mmp2^tm1Ito Timp3^tm1Osya/Timp3^tm1Osya involves: 129P2/OlaHsd * C57BL/6	abnormal abdominal aorta morphology	J:193744
	abnormal aorta wall morphology	J:193744
	aortitis	J:193744
	increased susceptibility to induced aneurysm formation	J:193744
	increased susceptibility to induced morbidity/mortality	J:193744
Mmp2^tm1Ito/Mmp2^tm1Ito Timp4^tm1Vuo/Timp4^tm1Vuo involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6	normal cardiovascular system phenotype	J:165901
Mmp14^tm1Noda/Mmp14⁺ Mmp2^tm1Ito/Mmp2^tm1Ito Not Specified	decreased body weight	J:91198
Mmp14^tm1Noda/Mmp14^tm1Noda Mmp2^tm1Ito/Mmp2^tm1Ito Not Specified	abnormal blood vessel morphology	J:91198
	abnormal bone ossification	J:91198
	abnormal skeletal muscle morphology	J:91198
	abnormal skeleton morphology	J:91198
	cyanosis	J:91198
	decreased birth weight	J:91198
	delayed muscle development	J:91198
	neonatal lethality, complete penetrance	J:91198
	thin diaphragm muscle	J:91198

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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