About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mmp9
matrix metallopeptidase 9
MGI:97011
97 phenotypes from 5 alleles in 20 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Mmp9tm1Amr/Mmp9+
B6.Cg-Mmp9tm1Amr 		decreased myocardial infarct size J:102541
Mmp9tm1Amr/Mmp9tm1Amr
B6.Cg-Mmp9tm1Amr 		decreased myocardial infarct size J:102541
Mmp9tm1Arnd/Mmp9tm1Arnd
B6.129P2-Mmp9tm1Arnd 		decreased histamine level J:110450
increased prostaglandin level J:110450
increased vascular permeability J:110450
Mmp9tm1Arnd/Mmp9tm1Arnd
involves: 129P2/OlaHsd 		decreased litter size J:64545
decreased susceptibility to experimental autoimmune encephalomyelitis J:58833
reduced fertility J:64545
Mmp9tm1b(EUCOMM)Wtsi/Mmp9tm1b(EUCOMM)Wtsi
C57BL/6N-Mmp9tm1b(EUCOMM)Wtsi/Ics 		short tibia J:211773
Mmp9tm1Itoh/Mmp9tm1Itoh
involves: 129P2/OlaHsd * C57BL/6J 		decreased metastatic potential J:55823
Mmp9tm1Tvu/Mmp9tm1Tvu
129S6/SvEvTac-Mmp9tm1Tvu 		normal immune system phenotype J:113463
Mmp9tm1Tvu/Mmp9tm1Tvu
B6.129S6-Mmp9tm1Tvu 		abnormal tumor morphology J:105098
decreased tumor incidence J:105098
Mmp9tm1Tvu/Mmp9tm1Tvu
C3N.129S6-Mmp9tm1Tvu 		decreased susceptibility to bacterial infection J:150311
decreased susceptibility to induced arthritis J:150311
joint inflammation J:150311
joint swelling J:150311
Mmp9tm1Tvu/Mmp9tm1Tvu
either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * CD-1) 		abnormal long bone epiphyseal plate morphology J:47297
abnormal long bone hypertrophic chondrocyte zone J:47297
abnormal metatarsal bone morphology J:47297
abnormal trabecular bone morphology J:47297
decreased length of long bones J:47297
delayed bone ossification J:47297
increased width of hypertrophic chondrocyte zone J:47297
osteopetrosis J:47297
short femur J:47297
short tibia J:47297
Mmp9tm1Tvu/Mmp9tm1Tvu
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6J) 		abnormal angiogenesis J:95880
Mmp9tm1Tvu/Mmp9tm1Tvu
either: FVB.129S6-Mmp9tm1Tvu or (involves: 129S6/SvEvTac) 		abnormal response to cardiac infarction J:68211
Mmp9tm1Tvu/Mmp9tm1Tvu
FVB.129S6-Mmp9tm1Tvu 		abnormal neutrophil physiology J:104644
abnormal physiological neovascularization J:104786
abnormal response to cardiac infarction J:104786
decreased susceptibility to induced colitis J:104644
decreased susceptibility to xenobiotic induced morbidity/mortality J:104644
normal immune system phenotype J:104644
increased angiogenesis J:104786
increased heart ventricle muscle contractility J:104786
Mmp9tm1Tvu/Mmp9tm1Tvu
FVB.Cg-Mmp9tm1Tvu/J 		abnormal intestinal goblet cell morphology J:128322
abnormal response/metabolism to endogenous compounds J:147593
decreased susceptibility to Flaviviridae infection J:153406
decreased susceptibility to Flaviviridae infection induced morbidity/mortality J:153406
decreased susceptibility to injury J:133660, J:148923
enhanced blood-brain barrier function J:153406
hypoalgesia J:133660
increased body weight J:147593
increased tibialis anterior weight J:147593
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129/Sv * 129S6/SvEvTac 		decreased circulating interleukin-10 level J:55723
increased susceptibility to type IV hypersensitivity reaction J:55723
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac 		abnormal chemokine level J:84293
abnormal dendritic cell physiology J:84293
abnormal impulse conducting system conduction J:148442
abnormal induced retina neovascularization J:113620
abnormal Langerhans cell physiology J:76157
abnormal myelination J:105765
abnormal myocardial fiber physiology J:148442
abnormal vascular smooth muscle physiology J:109006
abnormal vascular wound healing J:109006
cardiac fibrosis J:148442
decreased cardiac muscle contractility J:148442
decreased dendritic cell number J:84293
decreased IgE level J:84293
decreased inflammatory response J:84293
decreased oligodendrocyte number J:105765
decreased physiological sensitivity to xenobiotic J:84293
decreased susceptibility to induced aneurysm formation J:62760
decreased susceptibility to injury J:79422, J:91478, J:114188
increased circulating interferon-beta level J:148442
increased circulating interferon-gamma level J:148442
increased heart left ventricle posterior wall thickness J:148442
increased susceptibility to dystrophic cardiac calcinosis J:148442
increased susceptibility to Picornaviridae infection J:148442
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:148442
myocarditis J:148442
thick interventricular septum J:148442
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * C57BL/6 		abnormal chemokine level J:88065
abnormal cytokine secretion J:88065
abnormal leukocyte morphology J:88065
abnormal response to infection J:126519
decreased interferon-gamma secretion J:88065
increased eosinophil cell number J:88065
increased IgE level J:88065
increased interferon-gamma secretion J:88065
increased interleukin-4 secretion J:88065
increased interleukin-5 secretion J:88065
increased interleukin-13 secretion J:88065
increased lymphocyte cell number J:88065
increased macrophage cell number J:88065
increased monocyte cell number J:88065
increased T cell proliferation J:88065
increased T-helper 2 cell number J:88065
lung inflammation J:88065
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac 		impaired contextual conditioning behavior J:105763
reduced long-term potentiation J:105763
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * C57BL/6J 		abnormal angiogenesis J:101783
abnormal vascular smooth muscle physiology J:101783
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * CD-1 		abnormal bone marrow cell physiology J:149957
abnormal hematopoietic stem cell morphology J:149957
abnormal megakaryocyte differentiation J:149957
abnormal retina apoptosis J:129161
decreased susceptibility to injury J:129161
decreased susceptibility to ischemic brain injury J:79535
impaired hematopoiesis J:149957
impaired myelopoiesis J:149957
increased susceptibility to xenobiotic induced morbidity/mortality J:149957
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * FVB/N 		decreased neuron apoptosis J:96548
delayed wound healing J:150790
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory