Mpo Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mpo
myeloperoxidase
MGI:97137

12 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mpo^tm1Lus/Mpo^tm1Lus B6.129X1-Mpo^tm1Lus	abnormal muscle fiber morphology	J:112488
	abnormal neutrophil physiology	J:112488
	abnormal response to injury	J:112488
Mpo^tm1Lus/Mpo^tm1Lus involves: 129X1/SvJ	atherosclerotic lesions	J:112270
Mpo^tm1Lus/Mpo^tm1Lus involves: 129X1/SvJ * C57BL/6J	abnormal neutrophil physiology	J:67586
	atherosclerotic lesions	J:67586
	decreased inflammatory response	J:102688
	increased monocyte cell number	J:67586
	increased physiological sensitivity to xenobiotic	J:102688
	increased susceptibility to experimental autoimmune encephalomyelitis	J:102965
	increased susceptibility to fungal infection	J:67586
	increased susceptibility to induced morbidity/mortality	J:67586, J:126649
	sepsis	J:126649
Mpo^tm1Mae/Mpo^tm1Mae involves: 129P2/OlaHsd * C57BL/6	abnormal metabolism	J:53993
	abnormal neutrophil physiology	J:53993
	increased susceptibility to fungal infection	J:53993

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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