About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mpv17
MpV17 mitochondrial inner membrane protein
MGI:97138
74 phenotypes from 2 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Mpv17/Mpv17
CFW-Mpv17/J 		abnormal auditory brainstem response J:48661
abnormal blood homeostasis J:10661
abnormal coat/hair pigmentation J:143355
abnormal cochlea morphology J:48653
abnormal glomerular capillary morphology J:10661
abnormal hepatocyte morphology J:143355
abnormal hypodermis muscle layer morphology J:143355
abnormal liver lobule morphology J:143355
abnormal liver sinusoid morphology J:143355
abnormal mitochondrial crista morphology J:143355
abnormal portal triad morphology J:143355
abnormal renal glomerulus morphology J:108252, J:143355
abnormal renal tubule morphology J:108252
abnormal renal/urinary system physiology J:59102
abnormal scala media morphology J:48653
abnormal sebaceous gland morphology J:143355
abnormal skin morphology J:143355
albuminuria J:62419, J:108252
anemia J:10661
cachexia J:10661
normal cellular phenotype J:143355
cochlear ganglion degeneration J:48662
cochlear ganglion hypoplasia J:48653
cochlear outer hair cell degeneration J:48662
cortical renal glomerulopathies J:10661, J:108252
decreased body weight J:143355
decreased circulating serum albumin level J:10661, J:62419
decreased erythrocyte cell number J:10661
decreased hair follicle number J:143355
decreased hemoglobin content J:10661
decreased hepatocyte mitochondrial DNA content J:143355
decreased locomotor activity J:10661
decreased mitochondrial DNA content J:143355
decreased muscle fiber mitochondrial DNA content J:143355
decreased subcutaneous adipose tissue amount J:143355
decreased urine osmolality J:59102
dilated mitochondrion J:143355
dilated renal tubule J:10661
expanded mesangial matrix J:108252
fused podocyte foot processes J:10661
glomerulosclerosis J:10661, J:143355
normal homeostasis/metabolism phenotype J:143355
hypertension J:59102
increased blood urea nitrogen level J:10661
increased circulating alanine transaminase level J:143355
increased circulating aspartate transaminase level J:143355
increased circulating cholesterol level J:10661
increased circulating creatine kinase level J:143355
increased circulating creatinine level J:10661
increased circulating lactate level J:143355
increased heart rate J:59102
increased kidney weight J:62419
increased or absent threshold for auditory brainstem response J:48661
increased urine protein level J:10661, J:108252, J:143355
increased urine sodium level J:59102
kidney degeneration J:143355
kidney failure J:48662
normal liver/biliary system phenotype J:143355
organ of Corti degeneration J:48653, J:48662
podocyte foot process effacement J:108252
polyuria J:59102
premature death J:10661, J:27358, J:62419, J:143355
renal glomerulus hypertrophy J:10661, J:108252
renal interstitial fibrosis J:143355
sensorineural hearing loss J:48661, J:48662
small sebaceous gland J:143355
spiral ligament degeneration J:48653, J:48662
stria vascularis degeneration J:48653, J:48662
thin epidermis J:143355
thin skin J:143355
Mpv17em1(IMPC)J/Mpv17em1(IMPC)J
C57BL/6NJ-Mpv17em1(IMPC)J/J 		decreased circulating glucose level J:211773
decreased mean corpuscular hemoglobin J:211773
increased blood urea nitrogen level J:211773
increased heart weight J:211773
thrombocytopenia J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory