Mrc1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mrc1
mannose receptor, C type 1
MGI:97142

10 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mrc1^tm1Jub/Mrc1⁺ involves: 129X1/SvJ * C57BL/6J	abnormal circulating estrogen level	J:74332
	decreased litter size	J:74332
	impaired embryo implantation	J:74332
	increased circulating luteinizing hormone level	J:74332
Mrc1^tm1Jub/Mrc1^tm1Jub involves: 129X1/SvJ * C57BL/6J	embryonic lethality between implantation and somite formation, complete penetrance	J:74332
Mrc1^tm1Mnz/Mrc1^tm1Mnz B6.129P2-Mrc1^tm1Mnz	decreased susceptibility to parasitic infection	J:194065
	decreased susceptibility to parasitic infection induced morbidity/mortality	J:194065
	decreased T cell number	J:194065
	increased granulocyte number	J:194065
Mrc1^tm1Mnz/Mrc1^tm1Mnz involves: 129P2/OlaHsd	abnormal macrophage physiology	J:124290

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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