Msx1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Msx1
msh homeobox 1
MGI:97168

57 phenotypes from 6 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Msx1^{tm1b(KOMP)Wtsi}/Msx1⁺ C57BL/6N-Msx1^{tm1b(KOMP)Wtsi}/J	decreased thigmotaxis	J:211773
	increased circulating free fatty acids level	J:211773
	increased heart weight	J:211773
Msx1^{tm1b(KOMP)Wtsi}/Msx1^{tm1b(KOMP)Wtsi} C57BL/6N-Msx1^{tm1b(KOMP)Wtsi}/J	abnormal facial morphology	J:211773
	cleft palate	J:211773
	cyanosis	J:211773
	preweaning lethality, complete penetrance	J:211773
Msx1^tm1Bero/Msx1^tm1Bero B6.129P2-Msx1^tm1Bero	abnormal brain commissure morphology	J:84975
	abnormal brain morphology	J:84975
	abnormal cranium morphology	J:42035
	abnormal diencephalon morphology	J:84975
	abnormal palate morphology	J:42035
	abnormal roof plate morphology	J:84975
	abnormal subcommissural organ morphology	J:84975
	absent alveolar process	J:42035
	absent incisors	J:42035
	absent malleus processus brevis	J:42035
	absent molars	J:104286
	cleft chin	J:42035
	cleft secondary palate	J:42035, J:104286
	cyanosis	J:42035
	dilated fourth ventricle	J:84975
	dilated third ventricle	J:84975
	growth retardation of molars	J:42035
	hydrocephaly	J:84975
	normal limbs/digits/tail phenotype	J:42035
	neonatal lethality, complete penetrance	J:42035
	palatal shelf hypoplasia	J:104286
	respiratory distress	J:42035
	short snout	J:42035
	shortened head	J:42035
Msx1^tm1Bero/Msx1^tm1Bero involves: 129P2/OlaHsd	increased neuron number	J:99936
Msx1^tm1Rem/Msx1^tm1Rem Tg(Msx2-cre)5Rem/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	cleft palate	J:128624
Msx1^tm1Rilm/Msx1^tm1Rilm either: (involves: 129S4/SvJae-Msx1^tm1Rilm) or (involves: 129S4/SvJae * BALB/c) or (involves: 129X1/SvJae * C57BL/6J)	abnormal breathing pattern	J:17489
	abnormal cranium morphology	J:17489
	abnormal frontal bone morphology	J:17489
	abnormal mandible morphology	J:17489
	abnormal metopic suture morphology	J:17489
	abnormal palatal shelf fusion at midline	J:17489
	abnormal tooth morphology	J:17489
	absent alveolar process	J:17489
	absent gastric milk in neonates	J:17489
	absent lower incisors	J:17489
	absent malleus processus brevis	J:17489
	absent maxillary shelf	J:17489
	absent palatine bone horizontal plate	J:17489
	absent premaxilla	J:17489
	absent upper incisors	J:17489
	cleft secondary palate	J:17489
	cyanosis	J:17489
	growth retardation of molars	J:17489
	large anterior fontanelle	J:17489
	neonatal lethality, complete penetrance	J:17489
	overlapping parietal bones	J:17489
	short malleus	J:17489
	short mandible	J:17489
	short maxilla	J:17489
	small nasal bone	J:17489
Msx1^tm1Rilm/Msx1^tm1Rilm involves: 129S4/SvJae	abnormal epitympanic recess morphology	J:59750
Msx1^tm1Rilm/Msx1^tm1Rilm involves: 129S4/SvJae	absent malleus processus brevis	J:59750
Msx1^tm1Rilm/Msx1^tm1Rilm involves: 129S4/SvJae * BALB/c * CD-1	normal cardiovascular system phenotype	J:139946
Msx1^tm1Rilm/Msx1^tm1Rilm involves: 129S4/SvJae * CD-1	cleft palate	J:311535
Msx1^{tm2.1(cre/ERT2)Bero}/Msx1^tm1Bero involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal embryonic tissue morphology	J:194129
	abnormal eye morphology	J:194129
	abnormal facial morphology	J:194129
	abnormal liver development	J:194129
	exencephaly	J:194129
	thoracoabdominoschisis	J:194129
Msx1^tm3.1Bero/Msx1^tm3.1Bero Not Specified	no abnormal phenotype detected	J:208848

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