Msx2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Msx2
msh homeobox 2
MGI:97169

64 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Foxn1^nu/Foxn1^nu Msx2^tm1Rilm/Msx2^tm1Rilm involves: 129S4/SvJae * BALB/c * CD-1	abnormal nail bed morphology	J:173664
	abnormal nail matrix morphology	J:173664
	abnormal nail morphology	J:173664
	abnormal nail plate morphology	J:173664
	deformed nails	J:173664
	short nails	J:173664
Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Msx2^tm1Rilm/Msx2^tm1Rilm H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S4/SvJae * C57BL/6J * CBA/J	fused cornea and lens	J:184697
Msx1^tm1Bero/Msx1^tm1Bero Msx2^tm1Bero/Msx2^tm1Bero involves: 129 * 129P2/OlaHsd * C57BL/6 * C57BL/6J	decreased brain size	J:84975
	decreased embryo size	J:84975
	embryonic lethality during organogenesis, incomplete penetrance	J:84975
	exencephaly	J:84975
	spina bifida	J:84975
Msx1^tm1Bero/Msx1^tm1Bero Msx2^tm1Bero/Msx2^tm1Bero involves: 129/Sv * 129P2/OlaHsd	abnormal neural tube morphology	J:208848
	decreased embryo size	J:208848
	decreased spinal cord size	J:208848
Msx1^tm1Bero/Msx1^tm1Bero Msx2^tm1Bero/Msx2^tm1Bero involves: 129/Sv * C57BL/6 * NMRI	abnormal apical ectodermal ridge morphology	J:98917
	abnormal carpal bone morphology	J:98917
	abnormal pelvic girdle bone morphology	J:98917
	abnormal tarsal bone morphology	J:98917
	absent pubis	J:98917
	interdigital webbing	J:98917
	lethality throughout fetal growth and development, complete penetrance	J:98917
	oligodactyly	J:98917
	polydactyly	J:98917
	short limbs	J:98917
	small limb buds	J:98917
	small scapula	J:98917
Msx1^tm1Bero/Msx1^tm1Bero Msx2^tm1Bero/Msx2^tm1Yvla involves: 129/Sv * BALB/c * C57BL/6 * SJL	abnormal craniofacial development	J:136241
	cleft palate	J:136241
	perinatal lethality	J:136241
	short snout	J:136241
Msx1^tm1Bero/Msx1^tm1Bero Msx2^tm1Bero/Msx2^tm1Yvla Tagln^tm2(cre)Yec/Tagln⁺ involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac * NMRI	abnormal artery morphology	J:173525
	abnormal carotid artery morphology	J:173525
	abnormal vertebral artery morphology	J:173525
	intracranial aneurysm	J:173525
	intracranial hemorrhage	J:173525
	vascular smooth muscle hypoplasia	J:173525
Msx1^tm1Bero/Msx1^tm1Bero Msx2^tm1Yvla/Msx2^tm1Yvla involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6 * SJL	abnormal craniofacial morphology	J:136241
	abnormal limb development	J:136241
	exencephaly	J:136241
	lethality throughout fetal growth and development, complete penetrance	J:136241
	thoracoabdominoschisis	J:136241
Msx1^tm1Bero/Msx1^{tm2.1(cre/ERT2)Bero} Msx2^tm1Yvla/Msx2^tm1Yvla involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * NMRI	abnormal carotid artery morphology	J:173525
	vascular smooth muscle hypoplasia	J:173525
Msx1^tm1Rem/Msx1^tm1Rem Msx2^tm1Yvla/Msx2^tm1Yvla Tagln^tm2(cre)Yec/Tagln⁺ involves: 129S2/SvPas * 129S6/SvEvTac * NMRI	abnormal carotid artery morphology	J:173525
	vascular smooth muscle hypoplasia	J:173525
Msx1^tm1Rem/Msx1^tm1Rem Msx2^tm1Yvla/Msx2^tm1Yvla Tg(Tek-cre)1Ywa/0 involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * NMRI * SJL	normal cardiovascular system phenotype	J:173525
Msx1^tm1Rilm/Msx1⁺ Msx2^tm1Rilm/Msx2^tm1Rilm involves: 129S4/SvJae * CD-1	normal hearing/vestibular/ear phenotype	J:83306
Msx1^tm1Rilm/Msx1^tm1Rilm Msx2^tm1Rilm/Msx2⁺ involves: 129S4/SvJae * CD-1	normal hearing/vestibular/ear phenotype	J:83306
Msx1^tm1Rilm/Msx1^tm1Rilm Msx2^tm1Rilm/Msx2^tm1Rilm involves: 129S4/SvJae * BALB/c * CD-1	abnormal atrioventricular cushion morphology	J:139946
	abnormal cardiac epithelial to mesenchymal transition	J:139946
	abnormal heart valve morphology	J:139946
	abnormal mammary gland development	J:61509
	abnormal neurocranium morphology	J:61509
	arrest of tooth development	J:61509
	atrial septal defect	J:139946
	atrioventricular cushion hypoplasia	J:139946
	decreased hair follicle number	J:61509
Msx1^tm1Rilm/Msx1^tm1Rilm Msx2^tm1Rilm/Msx2^tm1Rilm involves: 129S4/SvJae * CD-1	abnormal external auditory canal morphology	J:83306
	abnormal malleus morphology	J:83306
	abnormal Meckel's cartilage morphology	J:83306
	abnormal middle ear ossicle morphology	J:83306
	absent malleus manubrium	J:83306
	absent malleus processus brevis	J:83306
	absent tympanic ring	J:83306
	small malleus	J:83306
Msx1^{tm2.1(cre/ERT2)Bero}/Msx1^{tm2.1(cre/ERT2)Bero} Msx2^tm1Bero/Msx2^tm1Bero involves: 129/Sv * 129P2/OlaHsd * 129S2/SvPas * C57BL/6	absent gastric milk in neonates	J:194129
	absent malleus processus brevis	J:194129
	absent teeth	J:194129
	cleft secondary palate	J:194129
	neonatal lethality	J:194129
Msx2^tm1Rilm/Msx2⁺ Twist1^tm1Bhr/Twist1⁺ involves: 129S4/SvJae * 129S7/SvEvBrd * BALB/c * C57BL/6	frontal bone foramen	J:87044
	polydactyly	J:87044
Msx2^tm1Rilm/Msx2^tm1Rilm Tg(Pax6-cre,GFP)1Pgr/0 involves: 129S4/SvJae * FVB	fused cornea and lens	J:184697
	microphthalmia	J:184697

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