Myb Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myb
myeloblastosis oncogene
MGI:97249

32 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ep300^tm1Pkb/Ep300⁺ Myb^tm1Ssp/Myb⁺ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal megakaryocyte morphology	J:98329
	decreased thymocyte number	J:98329
	thrombocytosis	J:98329
Lrfn2^{Tg(CD2-Myb/en)5Kmw}/Lrfn2⁺ involves: C57BL/10 * CBA	abnormal bone marrow cell morphology/development	J:125805
	abnormal common myeloid progenitor cell morphology	J:125805
	abnormal lymph node morphology	J:125805
	decreased T cell number	J:126456
	decreased T cell proliferation	J:126456
Lrfn2^{Tg(CD2-Myb/en)5Kmw}/Lrfn2⁺ Tg(H2-K-Myc)1Brn/? involves: C57BL/10 * CBA * FVB/N	abnormal bone marrow cell morphology/development	J:125805
	abnormal common myeloid progenitor cell morphology	J:125805
	abnormal erythropoiesis	J:125805
	abnormal lymph node morphology	J:125805
	enlarged lymph nodes	J:125805
	enlarged spleen	J:125805
	extramedullary hematopoiesis	J:125805
	lymph node hemorrhage	J:125805
	lymph node necrosis	J:125805
	premature death	J:125805
	spleen hyperplasia	J:125805
Lrfn2^{Tg(CD2-Myb/en)5Kmw}/Lrfn2^{Tg(CD2-Myb/en)5Kmw} involves: C57BL/10 * CBA	abnormal thymus cortex morphology	J:126456
	abnormal thymus medulla morphology	J:126456
	decreased CD8-positive, alpha-beta T cell number	J:126456
	decreased double-negative T cell number	J:126456
	decreased T cell number	J:126456
	decreased T cell proliferation	J:126456
	small spleen	J:126456
	small thymus	J:126456
Mpl^tm1Wsa/Mpl^tm1Wsa Myb^Plt3/Myb⁺ involves: 129S1/Sv * C57BL/6	abnormal definitive hematopoiesis	J:89601
	abnormal megakaryocyte differentiation	J:89601
	abnormal thrombopoiesis	J:89601
	thrombocytosis	J:89601
Mpl^tm1Wsa/Mpl^tm1Wsa Myb^Plt3/Myb^Plt3 involves: 129S1/Sv * C57BL/6	abnormal B cell differentiation	J:89601
	abnormal definitive hematopoiesis	J:89601
	abnormal erythropoiesis	J:89601
	abnormal megakaryocyte differentiation	J:89601
	abnormal spleen morphology	J:89601
	abnormal thrombopoiesis	J:89601
	anemia	J:89601
	decreased spleen B cell follicle size	J:89601
	increased spleen red pulp amount	J:89601
	perinatal lethality, incomplete penetrance	J:89601
	thrombocytosis	J:89601
Mpl^tm1Wsa/Mpl^tm1Wsa Myb^Plt4/Myb⁺ involves: 129S1/Sv * C57BL/6	abnormal definitive hematopoiesis	J:89601
	abnormal megakaryocyte differentiation	J:89601
	abnormal thrombopoiesis	J:89601
	thrombocytosis	J:89601
Mpl^tm1Wsa/Mpl^tm1Wsa Myb^Plt4/Myb^Plt4 involves: 129S1/Sv * C57BL/6	abnormal definitive hematopoiesis	J:89601
	abnormal erythropoiesis	J:89601
	abnormal megakaryocyte differentiation	J:89601
	abnormal spleen morphology	J:89601
	abnormal thrombopoiesis	J:89601
	anemia	J:89601
	decreased leukocyte cell number	J:89601
	decreased spleen B cell follicle size	J:89601
	increased spleen red pulp amount	J:89601
	thrombocytosis	J:89601

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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