Myf5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myf5
myogenic factor 5
MGI:97252

32 phenotypes from 10 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myf5^tm1(cre)Mrc/Myf5^tm1(cre)Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:120967
Myf5^{tm1(cre/Esr1)Trdo}/Myf5⁺ involves: 129S1/Sv 129X1/SvJ * C57BL/6 * FVB	no abnormal phenotype detected	J:199482
Myf5^tm1Jae/Myf5^tm1Jae either: 129-Myf5^tm1Jae or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	abnormal muscle morphology	J:3013
	abnormal myotome development	J:3013
	abnormal somite development	J:3013
	abnormal sternocostal joint morphology	J:3013
	abnormal sternum ossification	J:3013
	neonatal lethality, complete penetrance	J:3013
	respiratory failure	J:3013
	short ribs	J:3013
	short sternum	J:3013
Myf5^tm1Jae/Myf5^tm1Jae involves: 129S4/SvJae	abnormal sternocostal joint morphology	J:24360
	abnormal sternum ossification	J:24360
	absent myotome	J:42453
	rib bifurcation	J:42453
	short ribs	J:24360, J:31636, J:42453
Myf5^tm1Jae/Myf5^tm1Jae involves: 129S4/SvJae * C57BL/6J	fusion of vertebral arches	J:65301
Myf5^tm1Pas/Myf5^tm1Pas involves: 129 * C57BL/6 * DBA/2	abnormal muscle precursor cell migration	J:92799
	abnormal skeletal muscle morphology	J:92799
	absent myotome	J:92799
Myf5^tm1Pas/Myf5^tm1Pas Not Specified	abnormal eye muscle development	J:150130
	absent extraocular muscles	J:150130
	delayed somite formation	J:150130
Myf5^tm1Tajb/Myf5^tm1Tajb involves: 129/Sv * C57BL/6 * DBA/2	abnormal muscle precursor cell migration	J:92799
	abnormal skeletal muscle morphology	J:92799
	absent myotome	J:92799
Myf5^tm1Tajb/Myf5^tm1Tajb involves: 129S2/SvPas	abnormal eye muscle development	J:150130
Myf5^tm2Pas/Myf5^tm2Pas involves: 129S2/SvPas	abnormal respiration	J:66277
	abnormal rib development	J:66277
	neonatal lethality, complete penetrance	J:66277
Myf5^tm2Pas/Myf5^tm2Tajb involves: 129S2/SvPas	abnormal muscle regeneration	J:128921
Myf5^tm2Tajb/Myf5^tm2Tajb involves: 129/Sv * C57BL/6 * DBA/2	abnormal muscle precursor cell migration	J:92799
	abnormal skeletal muscle morphology	J:92799
	absent myotome	J:92799
Myf5^tm2Tajb/Myf5^tm2Tajb involves: 129S2/SvPas	abnormal eye muscle development	J:150130
	abnormal muscle regeneration	J:128921
	abnormal skeletal muscle morphology	J:128921
	abnormal skeletal muscle satellite cell proliferation	J:128921
	centrally nucleated skeletal muscle fibers	J:128921
	normal homeostasis/metabolism phenotype	J:168843
	increased skeletal muscle fiber diameter	J:128921
	increased variability of skeletal muscle fiber size	J:128921
	normal muscle phenotype	J:168843
	skeletal muscle fibrosis	J:128921
Myf5^tm3(cre)Sor/Myf5^tm3(cre)Sor involves: 129S4/SvJae * C57BL/6J	abnormal rib development	J:65301
	cervical vertebral fusion	J:65301
	thoracic vertebral fusion	J:65301
Myf5^{tm3(Myod1)Tajb}/Myf5^{tm3(Myod1)Tajb} Not Specified	normal vision/eye phenotype	J:150130
Myf5^tm3.1Thbr/Myf5^tm1Jae involves: 129S4/SvJae	normal skeleton phenotype	J:63517
Myf5^tm3.1Thbr/Myf5^tm3.1Thbr Not Specified	abnormal myotome development	J:63517
Myf5^tm3.1Thbr/Myf5^tm3.1Thbr Not Specified	normal skeleton phenotype	J:63517

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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