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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Myf5
myogenic factor 5
MGI:97252
147 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Abl1tm1Gcos/Abl1+
Myf5tm2Tajb/Myf5tm2Tajb
Myf6tm1Tajb/Myf6tm1Tajb
Myod1tm2.1(icre)Glh/Myod1+
involves: 129S * 129X1/SvJ * C57BL/6J 		abnormal myogenesis J:168843
decreased physiological sensitivity to xenobiotic J:168843
Atp11atm1c(KOMP)Wtsi/Atp11atm1c(KOMP)Wtsi
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJaeSor * C57BL/6JJcl * C57BL/6N 		abnormal myoblast differentiation J:262981
abnormal skeletal muscle regeneration J:262981
normal muscle phenotype J:262981
Bcl9tm1.1Agt/Bcl9tm1.1Agt
Bcl9ltm1.1Agt/Bcl9ltm1.1Agt
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 		abnormal muscle development J:154476
decreased skeletal muscle fiber size J:154476
impaired skeletal muscle regeneration J:154476
Col1a1tm3(tetO-Mirlet7g/Mir21)Gqda/Col1a1+
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		decreased body length J:199720
decreased body size J:199720
Crppaem2Mbp/Crppaem2Mbp
Myf5tm3(cre)Sor/Myf5+
B6.Cg-Myf5tm3(cre)Sor Crppaem2Mbp 		abnormal skeletal muscle morphology J:324289
centrally nucleated skeletal muscle fibers J:324289
decreased body weight J:324289
decreased grip strength J:324289
decreased skeletal muscle weight J:324289
dystrophic muscle J:324289
increased circulating creatine kinase level J:324289
increased variability of skeletal muscle fiber size J:324289
premature death J:324289
skeletal muscle fiber necrosis J:324289
skeletal muscle fibrosis J:324289
slow postnatal weight gain J:324289
Dlk1tm1.1Jvs/Dlk1+
Myf5tm3(cre)Sor/Myf5+
involves: 129P2/SvPas * 129S4/SvJaeSor * C57BL/6 * FVB/N 		abnormal cell differentiation J:167124
decreased body weight J:167124
decreased brown adipose tissue mass J:167124
decreased cell proliferation J:167124
decreased skeletal muscle fiber number J:167124
impaired skeletal muscle regeneration J:167124
increased inflammatory response J:167124
increased skeletal muscle fiber diameter J:167124
increased skeletal muscle fiber size J:167124
maternal imprinting J:167124
skeletal muscle fibrosis J:167124
Dmdmdx-4Cv/Dmdmdx-4Cv
Myf5tm2Tajb/Myf5tm2Tajb
involves: 129S2/SvPas * C3H/HeHa * C57BL * M. m. castaneus * M. m. musculus 		increased skeletal muscle fiber diameter J:128921
skeletal muscle fiber necrosis J:128921
Ehmt1tm1.1Tara/Ehmt1tm1.1Tara
Myf5tm3(cre)Sor/Myf5+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 		decreased brown fat cell size J:207678
decreased brown fat lipid droplet number J:207678
decreased interscapular fat pad weight J:207678
Elmo1tm1.2Ravi/Elmo1tm1.2Ravi
Elmo2tm1c(EUCOMM)Hmgu/Elmo2tm1c(EUCOMM)Hmgu
Myf5tm3(cre)Sor/Myf5+
involves: 129P2/OlaHsd * C57BL/6N 		abnormal muscle development J:331473
lethality during fetal growth through weaning, complete penetrance J:331473
Elmo2tm1c(EUCOMM)Hmgu/Elmo2tm1c(EUCOMM)Hmgu
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJaeSor * C57BL/6N 		preweaning lethality, incomplete penetrance J:331473
Erbb2tm1Haus/Erbb2tm1Klee
Gfra1tm3Jmi/Gfra1+
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJae * 129S4/SvJaeSor * 129X1/SvJ 		abnormal cholinergic neuron morphology J:160727
decreased motor neuron number J:160727
Erbb2tm1Haus/Erbb2tm1Klee
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJae * C57BL/6 		abnormal excitatory postsynaptic potential J:147957
abnormal gait J:147957
abnormal muscle spindle morphology J:147957
abnormal posture J:147957
abnormal sensory neuron innervation pattern J:147957
ataxia J:147957
decreased muscle spindle number J:147957
Fktntm1Kcam/Fktntm1Kcam
Myf5tm3(cre)Sor/Myf5+
involves: 129S/SvEv * 129S4/SvJaeSor 		decreased body weight J:187144
decreased grip strength J:187144
dystrophic muscle J:187144
increased circulating creatine kinase level J:187144
premature death J:187144
Fktntm3.1Ttd/Fktntm3.1Ttd
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJaeSor * C57BL/6 		abnormal muscle precursor cell morphology J:198535
abnormal muscle precursor cell physiology J:198535
centrally nucleated skeletal muscle fibers J:198535
decreased body weight J:198535
decreased satellite cell number J:198535
decreased skeletal muscle weight J:198535
impaired skeletal muscle regeneration J:198535
increased circulating creatine kinase level J:198535
increased collagen deposition in the muscles J:198535
increased variability of skeletal muscle fiber size J:198535
postnatal growth retardation J:198535
premature death J:198535
skeletal muscle atrophy J:198535
skeletal muscle fibrosis J:198535
skeletal muscle necrosis J:198535
Gdnftm1.1Neas/Gdnftm1.1Neas
Myf5tm3(cre)Sor/Myf5+
involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 * SJL 		abnormal cholinergic neuron morphology J:160727
decreased motor neuron number J:160727
Gt(ROSA)26Sortm1(DTA)Lky/Gt(ROSA)26Sor+
Myf5tm3(cre)Sor/Myf5+
involves: 129P2/OlaHsd * 129S4/SvJaeSor 		abnormal levator veli palatini muscle morphology J:310908
abnormal palatopharyngeus muscle morphology J:310908
abnormal soft palate morphology J:310908
abnormal soft palate muscle morphology J:310908
abnormal superior pharyngeal constrictor muscle morphology J:310908
abnormal tensor veli palatini muscle morphology J:310908
decreased palatal shelf size J:310908
lethality throughout fetal growth and development, complete penetrance J:310908
Gt(ROSA)26Sortm1(DTA)Mrc/Gt(ROSA)26Sor+
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129X1/SvJ 		abnormal rib morphology J:133338
asymmetric sternocostal joints J:133338
normal mortality/aging J:133338
rib fusion J:133338
Gt(ROSA)26Sortm1(DTA)Mrc/Gt(ROSA)26Sor+
Myf5tm1.1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129X1/SvJ 		abnormal rib morphology J:133338
normal muscle phenotype J:133338
neonatal lethality, complete penetrance J:133338
Gt(ROSA)26Sortm1(DTA)Mrc/Gt(ROSA)26Sortm1(DTA)Mrc
Myf5tm1(cre)Mrc/Myf5tm1(cre)Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased body size J:120967
weakness J:120967
Gt(ROSA)26Sortm2(SS18)Mrc/Gt(ROSA)26Sortm2(SS18)Mrc
Myf5tm1(cre)Mrc/Myf5tm1(cre)Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased body size J:120967
increased sarcoma incidence J:120967
increased tumor incidence J:120967
postnatal lethality, incomplete penetrance J:120967
Gt(ROSA)26Sortm3(SS18/EGFP)Mrc/Gt(ROSA)26Sortm3(SS18/EGFP)Mrc
Myf5tm1(cre)Mrc/Myf5tm1(cre)Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal muscle development J:120967
decreased body size J:120967
increased sarcoma incidence J:120967
increased tumor incidence J:120967
postnatal lethality, incomplete penetrance J:120967
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased body size J:194308
myopathy J:194308
premature death J:194308
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJaeSor * C57BL/6J 		abnormal brown fat cell differentiation J:207891
abnormal muscle morphology J:207891
decreased brown adipose tissue amount J:207891
decreased muscle weight J:207891
neonatal lethality, complete penetrance J:207891
respiratory failure J:207891
Lbx1tm1.1Khan/Lbx1tm1.1Khan
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJaeSor * C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj 		abnormal muscle precursor cell migration J:178868
abnormal skeletal muscle morphology J:178868
decreased body size J:178868
Lgals1tm1Rob/Lgals1tm1Rob
Myf5tm2Pas/Myf5+
involves: 129S/SvEv * 129S2/SvPas 		abnormal skeletal muscle fiber morphology J:119480
decreased skeletal muscle fiber diameter J:119480
delayed muscle development J:119480
delayed skeletal muscle regeneration J:119480
Lin28atm1Gqda/Lin28atm1Gqda
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		normal growth/size/body region phenotype J:199720
Lin28atm1Gqda/Lin28atm1Gqda
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJae * C57BL/6 * CD-1 		impaired glucose tolerance J:177113
insulin resistance J:177113
Lin28btm1Gqda/Lin28btm1Gqda
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		decreased body size J:199720
impaired glucose tolerance J:199720
insulin resistance J:199720
normal muscle phenotype J:199720
Lin28btm1Gqda/Lin28btm1Gqda
Myf5tm1(cre)Mrc/Myf5+
Tsc1tm1Djk/Tsc1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		normal growth/size/body region phenotype J:199720
Mecomtm1Miku/Mecomtm1Miku
Prdm16tm1.1Brsp/Prdm16tm1.1Brsp
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JCrlj 		abnormal interscapular fat pad morphology J:213153
increased brown fat cell lipid droplet size J:213153
Myf5tm1(cre)Mrc/Myf5+
Myod1tm1Jae/Myod1tm1Jae
Pax7tm1.1Thbr/Pax7tm1.1Thbr
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		decreased satellite cell number J:202693
Myf5tm1(Pdgfa)Sor/Myf5tm1(Pdgfa)Sor
involves: 129S4/SvJae * C57BL/6J 		abnormal rib morphology J:65301
abnormal thoracic cage morphology J:65301
fusion of vertebral arches J:65301
increased rib number J:65301
neonatal lethality, complete penetrance J:65301
Myf5tm1Jae/Myf5+
Myf6tm1Wb/Myf6+
involves: 129S1/Sv * 129S4/SvJae 		abnormal myotome development J:42453
abnormal rib morphology J:42453
abnormal sternebra morphology J:42453
abnormal sternocostal joint morphology J:42453
perinatal lethality, complete penetrance J:42453
respiratory distress J:42453
rib bifurcation J:42453
rib fusion J:42453
short ribs J:42453
Myf5tm1Jae/Myf5+
Myf6tm1Eno/Myf6+
involves: 129S4/SvJae * 129S7/SvEvBrd 		abnormal myotome development J:42453
abnormal rib morphology J:42453
abnormal sternocostal joint morphology J:42453
perinatal lethality, incomplete penetrance J:42453
Myf5tm1Jae/Myf5+
Myf6tm1Thbr/Myf6+
involves: 129S4/SvJae 		perinatal lethality, complete penetrance J:31636
short ribs J:31636
Myf5tm1Jae/Myf5tm1Jae
Myod1tm1.1Glh/Myod1+
involves: 129/Sv * 129S4/SvJae * C57BL/6J 		abnormal muscle development J:87370
Myf5tm1Jae/Myf5tm1Jae
Myod1tm1.1Glh/Myod1tm1.1Glh
involves: 129/Sv * 129S4/SvJae * C57BL/6J 		abnormal muscle development J:87370
Myf5tm1Pas/Myf5+
Myod1tm1Jae/Myod1tm1Jae
involves: 129 * C57BL/6 * DBA/2 		postnatal lethality J:92799
Myf5tm1Pas/Myf5tm1Pas
Myod1tm1Jae/Myod1+
involves: 129 * C57BL/6 * DBA/2 		postnatal lethality J:92799
Myf5tm1Pas/Myf5tm1Pas
Myod1tm1Jae/Myod1tm1Jae
involves: 129 * C57BL/6 * DBA/2 		abnormal myogenesis J:92799
absent skeletal muscle J:92799
postnatal lethality, complete penetrance J:92799
Myf5tm1Tajb/Myf5tm1Tajb
Myod1tm1Jae/Myod1tm1Jae
involves: 129/Sv * C57BL/6 * DBA/2 		abnormal myogenesis J:92799
absent skeletal muscle J:92799
postnatal lethality, complete penetrance J:92799
Myf5tm1Tajb/Myf5tm1Tajb
Pax7tm1.1Tajb/Pax7tm1.1Tajb
involves: 129S2/SvPas 		abnormal extraocular muscle morphology J:150130
normal muscle phenotype J:150130
Myf5tm2(Fgf6)Thbr/Myf5tm2(Fgf6)Thbr
Not Specified 		normal skeleton phenotype J:63517
Myf5tm2(Myog)Jae/Myf5tm2(Myog)Jae
involves: 129S4/SvJae 		no abnormal phenotype detected J:31611
Myf5tm2(Myog)Jae/Myf5tm2(Myog)Jae
involves: 129S4/SvJae * C57BL/6J 		abnormal myotome development J:65301
normal skeleton phenotype J:65301
Myf5tm2(Pdgfa)Sor/Myf5tm2(Pdgfa)Sor
involves: 129S4/SvJae * C57BL/6J 		abnormal cervical vertebrae morphology J:65301
abnormal myotome development J:65301
abnormal rib development J:65301
abnormal rib morphology J:65301
abnormal thoracic cage morphology J:65301
cervical vertebral fusion J:65301
increased bone ossification J:65301
increased rib number J:65301
neonatal lethality, complete penetrance J:65301
Myf5tm2Tajb/Myf5+
Tbx1tm1Pa/Tbx1tm1Pa
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ 		abnormal pharyngeal muscle morphology J:150130
Myf5tm2Tajb/Myf5tm2Tajb
Myf6tm1Tajb/Myf6+
involves: 129S2/SvPas * BALB/c * C57BL/6 		abnormal muscle development J:92799
Myf5tm2Tajb/Myf5tm2Tajb
Myf6tm1Tajb/Myf6tm1Tajb
involves: 129S2/SvPas 		abnormal extraocular muscle morphology J:150130
abnormal eye muscle development J:150130
Myf5tm2Tajb/Myf5tm2Tajb
Myod1tm1Jae/Myod1tm1Jae
involves: 129/Sv * C57BL/6 * DBA/2 		abnormal myogenesis J:92799
absent skeletal muscle J:92799
postnatal lethality, complete penetrance J:92799
Myf5tm2Tajb/Myf5tm2Tajb
Tbx1tm1Pa/Tbx1tm1Pa
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ 		abnormal pharyngeal muscle morphology J:150130
Myf5tm3(cre)Sor/Myf5+
Ntf3tm2Jae/Ntf3tm2Jae
involves: 129S1/Sv * C57BL/6 		abnormal gait J:147957
abnormal nervous system electrophysiology J:147957
abnormal posture J:147957
ataxia J:147957
Myf5tm3(cre)Sor/Myf5+
Stat5atm2Mam/Stat5atm2Mam
Stat5btm1Mam/Stat5btm1Mam
Tg(Alb1-cre)1Dlr/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N 		decreased body length J:119237
decreased body weight J:119237
decreased circulating insulin-like growth factor I level J:119237
decreased lean body mass J:119237
increased total body fat amount J:119237
Myf5tm3(cre)Sor/Myf5+
Stat5btm1Mam/Stat5btm1Mam
involves: 129S4/SvJaeSor * 129S6/SvEvTac 		decreased body length J:119237
decreased body weight J:119237
decreased circulating insulin-like growth factor I level J:119237
decreased lean body mass J:119237
impaired glucose tolerance J:119237
increased circulating triglyceride level J:119237
increased total body fat amount J:119237
Myf5tm3(cre)Sor/Myf5+
Stat5btm1Mam/Stat5btm1Mam
Tg(Alb1-cre)1Dlr/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N 		decreased body length J:119237
decreased body weight J:119237
decreased circulating insulin-like growth factor I level J:119237
decreased lean body mass J:119237
increased total body fat amount J:119237
Myf5tm3(cre)Sor/Myf5+
Tg(CAG-Nog)1Ych/0
involves: 129S4/SvJaeSor 		abnormal levator veli palatini muscle morphology J:310908
abnormal palatopharyngeus muscle morphology J:310908
abnormal soft palate muscle morphology J:310908
abnormal superior pharyngeal constrictor muscle morphology J:310908
abnormal tensor veli palatini muscle morphology J:310908
cleft soft palate J:310908
Myf5tm3(cre)Sor/Myf5+
Tg(ACTB-Edn1)721Clou/0
involves: 129S4/SvJaeSor * C57BL/6 		abnormal costal cartilage morphology J:221133
Myf5tm3(cre)Sor/Myf5+
Tg(ACTB-Edn1)1398Clou/0
involves: 129S4/SvJaeSor * C57BL/6 		abnormal costal cartilage morphology J:221133
rib fusion J:221133
Myf5tm3(cre)Sor/Myf5+
Tg(ACTB-Edn1)1408Clou/0
involves: 129S4/SvJaeSor * C57BL/6 		abnormal costal cartilage morphology J:221133
rib fusion J:221133
Myf5tm3(cre)Sor/Myf5+
Tg(ACTB-Edn1)1416Clou/0
involves: 129S4/SvJaeSor * C57BL/6 		abnormal costal cartilage morphology J:221133
rib fusion J:221133
upper jaw to lower jaw transformation J:221133
Myf5tm3(cre)Sor/Myf5+
Sik1tm1.1Berd/Sik1tm1.1Berd
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * SJL 		abnormal gluconeogenesis J:236223
abnormal glucose homeostasis J:236223
decreased circulating insulin level J:236223
improved glucose tolerance J:236223
increased insulin sensitivity J:236223
increased skeletal muscle cell glucose uptake J:236223
normal muscle phenotype J:236223
Myf5tm3(cre)Sor/Myf5+
Spin1tm1.1Rosc/Spin1tm1.1Rosc
involves: 129S4/SvJaeSor * C57BL/6N * C57BL/6NTac 		abnormal diaphragm morphology J:302851
abnormal forelimb morphology J:302851
abnormal M line morphology J:302851
abnormal myogenesis J:302851
abnormal neuromuscular synapse morphology J:302851
abnormal posture J:302851
abnormal skeletal muscle fiber morphology J:302851
abnormal skeletal muscle fiber type ratio J:302851
abnormal skeletal muscle morphology J:302851
abnormal soleus morphology J:302851
abnormal tibialis anterior morphology J:302851
absent gastric milk in neonates J:302851
cachexia J:302851
decreased body weight J:302851
decreased skeletal muscle fiber number J:302851
decreased skeletal muscle mass J:302851
increased skeletal muscle fiber size J:302851
neonatal lethality, incomplete penetrance J:302851
scoliosis J:302851
skeletal muscle degeneration J:302851
skeletal muscle fiber degeneration J:302851
skeletal muscle fiber necrosis J:302851
skeletal muscle fibrosis J:302851
Myf5tm3(cre)Sor/Myf5tm3(cre)Sor
Myod1tm1Jae/Myod1tm1Jae
involves: 129S4/SvJae * C57BL/6J 		abnormal myogenesis J:65301
abnormal myotube morphology J:65301
Myf5tm4(Myod1)Sor/Myf5tm4(Myod1)Sor
involves: 129S4/SvJae * C57BL/6J 		normal muscle phenotype J:65301
normal skeleton phenotype J:65301
Pax7tm1.1Thbr/Pax7tm1.1Thbr
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		decreased satellite cell number J:202693
Pax7tm1.1Thbr/Pax7tm1.1Thbr
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJaeSor 		decreased body size J:202693
decreased satellite cell number J:202693
decreased skeletal muscle fiber diameter J:202693
decreased skeletal muscle fiber number J:202693
impaired skeletal muscle regeneration J:202693
Prdm16tm1.1Brsp/Prdm16tm1.1Brsp
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal brown adipose tissue morphology J:213153
abnormal brown adipose tissue thermogenesis J:213153
abnormal cellular respiration J:213153
abnormal interscapular fat pad morphology J:213153
abnormal oxygen consumption J:213153
decreased body fat mass J:213153
decreased body length J:213153
decreased body weight J:213153
decreased brown fat lipid droplet number J:213153
decreased fat cell mitochondrial DNA content J:213153
decreased lean body mass J:213153
decreased mitochondrial number J:213153
impaired adaptive thermogenesis J:213153
improved glucose tolerance J:213153
increased brown fat cell lipid droplet size J:213153
increased interscapular fat pad weight J:213153
whitened brown adipose tissue morphology J:213153
Prox1tm2Gco/Prox1tm2Gco
Myf5tm3(cre)Sor/Myf5+
involves: 129S1/Sv * 129S4/SvJae * C57BL/6J 		abnormal skeletal muscle morphology J:212185
Stat5atm2Mam/Stat5atm2Mam
Stat5btm1Mam/Stat5btm1Mam
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJaeSor * 129S6/SvEvTac 		decreased body length J:119237
decreased body weight J:119237
decreased circulating insulin-like growth factor I level J:119237
decreased lean body mass J:119237
impaired glucose tolerance J:119237
increased circulating triglyceride level J:119237
increased total body fat amount J:119237
Zfp422em1Mode/Zfp422em1Mode
Myf5tm3(cre)Sor/Myf5+
involves: 129S4/SvJaeSor * C57BL/6J 		abnormal myoblast differentiation J:297035
abnormal skeletal muscle fiber morphology J:297035
decreased fetal weight J:297035
decreased skeletal muscle fiber size J:297035
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11/12/2024
MGI 6.24 		The Jackson Laboratory