Casp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Casp2
caspase 2
MGI:97295

23 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Casp2^em1(IMPC)Mbp/Casp2^em1(IMPC)Mbp C57BL/6NCrl-Casp2^em1(IMPC)Mbp/MbpMmucd	abnormal brain morphology	J:211773
	abnormal cecum morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged cecum	J:211773
	enlarged testis	J:211773
	increased brain size	J:211773
	increased startle reflex	J:211773
	persistence of hyaloid vascular system	J:211773
	small kidney	J:211773
Casp2^tm1Vaux/Casp2^tm1Vaux involves: 129S1/Sv * C57BL/6	normal cellular phenotype	J:103480
Casp2^tm1Yuan/Casp2^tm1Yuan involves: 129S4/SvJae * C57BL/6J * DBA/2	abnormal apoptosis	J:47601
	abnormal B cell apoptosis	J:47601
	abnormal facial motor nucleus morphology	J:47601
	abnormal female germ cell morphology	J:47601
	abnormal neuron apoptosis	J:47601
	abnormal oocyte morphology	J:47601
	abnormal sympathetic neuron morphology	J:47601
	increased primordial ovarian follicle number	J:47601

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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