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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nhlh2
nescient helix loop helix 2
MGI:97324
12 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Nhlh2tm2Thbr/Nhlh2tm2Thbr
Tg(Gnrh1-cre)1Dlc/0
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * CBA 		decreased neuron number J:199640
ectopic neuron J:199640
Nhlh1tm1Irk/Nhlh1tm1Irk
Nhlh2tm1Irk/Nhlh2+
involves: 129S4/SvJae * C57BL/6 		abnormal parasympathetic nervous system physiology J:78031
abnormal QT variability J:78031
abnormal reflex J:78031
decreased heart rate variability J:78031
irregular heartbeat J:78031
premature death J:78031
ventricular fibrillation J:78031
ventricular premature beat J:78031
Nhlh1tm1Irk/Nhlh1tm1Irk
Nhlh2tm1Irk/Nhlh2tm1Irk
involves: 129S4/SvJae * C57BL/6 		normal mortality/aging J:78031
Nhlh1tm1Thbr/Nhlh1tm1Thbr
Nhlh2tm1Thbr/Nhlh2tm1Thbr
involves: 129S4/SvJae 		abnormal neuron morphology J:93303
decreased neuron number J:93303
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory