Nppa Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nppa
natriuretic peptide type A
MGI:97367

22 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nppa^tm1Unc/Nppa⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal heart right ventricle pressure	J:64898
	heart right ventricle hypertrophy	J:64898
	salt-sensitive hypertension	J:76312
Nppa^tm1Unc/Nppa^tm1Unc involves: 129P2/OlaHsd * C57BL/6	abnormal cardiovascular system physiology	J:53877
	abnormal renal sodium reabsorption	J:95900
	abnormal renin activity	J:95900
	abnormal systemic arterial blood pressure	J:63072
	abnormal vascular resistance	J:53877
	abnormal vascular smooth muscle morphology	J:54986
	normal cardiovascular system phenotype	J:54986
	decreased cardiac output	J:53877
	decreased hematocrit	J:76312
	enlarged heart	J:76312
	heart left ventricle hypertrophy	J:54986
	heart right ventricle hypertrophy	J:54986, J:64898
	normal homeostasis/metabolism phenotype	J:57623
	hypertension	J:76312
	increased circulating adrenaline level	J:57623
	increased heart rate	J:57623
	increased heart weight	J:76312
	increased right ventricle peak pressure	J:54986, J:64898
	increased systemic arterial diastolic blood pressure	J:53877
	pulmonary hypertension	J:54986
	salt-sensitive hypertension	J:57623, J:95900

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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