Nppc Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nppc
natriuretic peptide type C
MGI:97369

33 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nppc^lbab/Nppc^lbab B6.PL-Nppc^lbab/GrsrJ	abnormal endochondral bone ossification	J:321139
	abnormal female meiosis	J:164870
	abnormal long bone epiphyseal plate proliferative zone	J:321139
	decreased body length	J:122924, J:321139
	decreased body size	J:321139
	decreased body weight	J:122924, J:321139
	decreased bone volume	J:321139
	decreased long bone epiphyseal plate size	J:321139
	decreased trabecular bone thickness	J:321139
	decreased width of hypertrophic chondrocyte zone	J:321139
	disproportionate dwarf	J:122924
	postnatal lethality, complete penetrance	J:122924
	short limbs	J:122924
Nppc^lbab/Nppc^lbab either: (involves: C57BL/6J * PL/J) or PL/J	abnormal long bone epiphyseal plate morphology	J:79175
	decreased body size	J:79175
	decreased length of long bones	J:79175
	disorganized long bone epiphyseal plate	J:79175
	disproportionate dwarf	J:79175
	normal reproductive system phenotype	J:79175
	short fibula	J:79175
	short tail	J:79175
	short tibia	J:79175
	small testis	J:79175
Nppc^lbab/Nppc^lbab involves: PL/J	abnormal sensory neuron innervation pattern	J:153212
Nppc^lbab/Nppc^lbab Tg(Col2a1-Nppc)1Yog/0 involves: C57BL/6J * PL/J	decreased body length	J:321139
	decreased body weight	J:321139
	decreased width of hypertrophic chondrocyte zone	J:321139
	normal skeleton phenotype	J:321139
Nppc^tm1.1Fgr/Nppc^tm1.1Fgr involves: 129P2/OlaHsd * C57BL/6J	abnormal miniature excitatory postsynaptic currents	J:153212
	abnormal neuron physiology	J:153212
	abnormal sensory neuron innervation pattern	J:153212
	decreased body height	J:153212
	decreased physiological sensitivity to xenobiotic	J:153212
Nppc^tm1.1Fgr/Nppc^tm1.1Fgr Tg(Thy1-YFP)HJrs/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA	abnormal sensory neuron innervation pattern	J:153212
Nppc^tm1Yog/Nppc^tm1Yog either: 129X1/SvJ or (involves: 129 * C57BL/6J)	abnormal cartilage morphology	J:75620
	abnormal long bone epiphyseal plate proliferative zone	J:75620
	abnormal vertebral epiphyseal plate morphology	J:75620
	decreased body length	J:75620
	decreased body weight	J:75620
	decreased cranium height	J:75620
	decreased long bone epiphyseal plate size	J:75620
	decreased width of hypertrophic chondrocyte zone	J:75620
	disproportionate dwarf	J:75620
	postnatal growth retardation	J:75620
	postnatal lethality, incomplete penetrance	J:75620
Nppc^tm1Yog/Nppc^tm1Yog Tg(Col2a1-Nppc)1Yog/0 either: 129X1/SvJ or (involves: 129 * C57BL/6J)	normal mortality/aging	J:75620
	normal skeleton phenotype	J:75620

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24