Odc1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Odc1
ornithine decarboxylase, structural 1
MGI:97402

24 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Odc1^{tm1b(EUCOMM)Hmgu}/Odc1⁺ C57BL/6N-Odc1^{tm1b(EUCOMM)Hmgu}/J	increased heart weight	J:211773
Odc1^{tm1b(EUCOMM)Hmgu}/Odc1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Odc1^{tm1b(EUCOMM)Hmgu}/J	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Odc1^tm1Jlc/Odc1⁺ involves: 129S1/Sv	no abnormal phenotype detected	J:71462
Odc1^tm1Jlc/Odc1^tm1Jlc involves: 129S1/Sv	abnormal inner cell mass apoptosis	J:71462
Odc1^tm1Jlc/Odc1^tm1Jlc involves: 129S1/Sv	embryonic lethality between implantation and somite formation, complete penetrance	J:71462
Tg(K6ODCtr)55Tgo/0 C57BL/6-Tg(K6ODCtr)55Tgo/J	abnormal hair follicle morphology	J:62356
	absent vibrissae	J:62356
	alopecia	J:62356
	decreased body weight	J:62356
	decreased subcutaneous adipose tissue amount	J:62356
	dermal cyst	J:62356
	dilated hair follicle infundibulum	J:62356
	hair follicle comedo	J:62356
	hair follicle degeneration	J:62356
	long nails	J:62356
	sebaceous gland hyperplasia	J:62356
	wrinkled skin	J:62356
Tg(K6ODCtr)55Tgo/0 involves: C3H * C57BL/6	absent hair follicles	J:29098
	absent vibrissae	J:29098
	alopecia	J:29098
	decreased body weight	J:29098
	decreased subcutaneous adipose tissue amount	J:29098
	dermal cyst	J:29098
	increased keratinocyte apoptosis	J:133302
	increased keratoacanthoma incidence	J:29098
	increased skin papilloma incidence	J:29098
	increased skin tumor incidence	J:29098
	long nails	J:29098
	oily skin	J:29098
	sebaceous gland hyperplasia	J:29098
	wrinkled skin	J:29098

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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